Herpes simplex viruses (HSVs) contain a function that can cause the degradation of host mRNA and mediate the shutoff of host protein synthesis. Previously, we observed that HSV infection causes a 40-fold increase in cholesteryl ester (CE) accretion in arterial smooth muscle cells due, in part, to a substantial decrease in CE hydrolysis. In studies reported herein, we found that HSV infection le...

The objective of this study is to create building damage hazard zonation area using fuzzy kohonen clustering network (FKCN) for physical parameter data clustering and inverse distance weighting (IDW) for data interpolation in Banda Aceh city, Indonesia. IDW algorithm is used alongside FKCN because of its simplicity. The physical parameter in this study consists of lithology, topographic zone an...

This case analyzes the reconstruction of the Indonesian provinces of Aceh and Nias following the devastating tsunami of December 2004 and subsequent earthquake in Nias in March 2005. The case focuses on community involvement in prioritization and sequencing of needs, planning and project implementation, and monitoring and evaluation of progress. Lessons can be drawn from the challenges of imple...

our previous experiments indicated that smooth muscle cells (SMC) in neointima of injured rabbit aorta (a) acquire the capacity to produce PGI2 and (b) have increased lysosomal CE hydrolytic (acid cholesteryl ester hydrolase [ACEH])activity. Using cultured SMC from rabbit thoracic aorta, we demonstrated that PGI2, 6-keto-PGF1,, and 6-keto-PGE, enhanced ACEH activity fourfold. No significant eff...

The Indonesian province of Aceh is known as rebellious. The most recent eruption was the civil war between the Indonesian army and the ethno-nationalist separatist movement GAM, which started in 1976 and could only be ended after the destructive Indian Ocean tsunami of 2004. Aceh is also known as strictly Islamic. When Aceh is featured in the media, the focus is often on the implementation, sin...

Stroke in low and middle income countries is an increasing cause of death and disability, with rates and the estimated burden considerably higher than that of high income countries. Lay explanatory models are believed to be one of the major influences on health seeking behaviour and essential to understand for appropriate education strategies. Despite stroke being a considerable health concern ...

Aims The aim of this study was to isolate and identify a cellulolytic bacterium from the rumen fluid of Aceh's cattle. Biodegradation by cellulolytic rumen bacteria can be used as a source of cellulolytic bacteria that act to degrade feed fibrous material so as to improve the quality of nutrients and digestibility of feed ingredients at a cheaper price than the use of commercial cellulase enzym...

The 2004 Indian Ocean earthquake and tsunami caused catastrophic damage to many cities on the rim of the Indian Ocean. Banda Aceh in Sumatra, Indonesia was particularly badly hit due to its close proximity to the epicenter. The Singapore Armed Forces Medical Team was one of the earliest medical teams to arrive in Banda Aceh, providing primary health care to the survivors. In the first 17 days o...

Objective: The differentiation of atypical complex type endometrial hyperplasia (ACEH) and low grade endometrial carcinoma (EC) may be problematic in endometrial biopsy materials. Desmoplasia and stromal invasion are diagnostic for EC but they are not always demonstrated in endometrial biopsies. In this study, we investigated the contribution of nuclear morphometry to distinction of ACEH and lo...

BACKGROUND The present qualitative study assessed the need, acceptability and appropriateness for implementing effective and culturally appropriate smoking prevention programs for adolescents in schools in Indonesia. METHODS Snowball sampling was used to recruit participants. The study sample comprised a mixture of staff in the education department, junior high school teachers and individuals...