نتایج جستجو برای: acceleration of 070 g

تعداد نتایج: 21201329  

2015
Georg Karpel-Massler Chang Shu Lily Chau Matei Banu Marc-Eric Halatsch Mike-Andrew Westhoff Yulian Ramirez Alonzo H. Ross Jeffrey N. Bruce Peter Canoll Markus D. Siegelin

Despite great efforts taken to advance therapeutic measures for patients with glioblastoma, the clinical prognosis remains grim. The antiapoptotic Bcl-2 family protein Mcl-1 is overexpressed in glioblastoma and represents an important resistance factor to the BH-3 mimetic ABT263. In this study, we show that combined treatment with ABT263 and GX15-070 overcomes apoptotic resistance in establishe...

2018
Stefan Just Bertrand L Chenard Angelo Ceci Timothy Strassmaier Jayhong A Chong Nathaniel T Blair Randall J Gallaschun Donato Del Camino Susan Cantin Marc D'Amours Christian Eickmeier Christopher M Fanger Carsten Hecker David P Hessler Bastian Hengerer Katja S Kroker Sam Malekiani Robert Mihalek Joseph McLaughlin Georg Rast JoAnn Witek Achim Sauer Christopher R Pryce Magdalene M Moran

BACKGROUND Forty million adults in the US suffer from anxiety disorders, making these the most common forms of mental illness. Transient receptor potential channel canonical subfamily (TRPC) members 4 and 5 are non-selective cation channels highly expressed in regions of the cortex and amygdala, areas thought to be important in regulating anxiety. Previous work with null mice suggests that inhi...

The accelerating fields (e. g. centrifugal acceleration and constant acceleration) can change the physical performance of nano-sensors significantly. Herein, a new size-dependent model is developed to investigate the scale-dependent dynamic behavior of nanowire-fabricated sensor operated in an accelerating field. The scale-dependent equation of motion is developed by employing a consolidation o...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد یزد - دانشکده شیمی 1392

in this study, a simple, rapid and selective method was developed for the determination of dexamethasone. the proposed method is based on inhibitory effect of dexamethasone on the oxidation of orange-g by bromate in sulfuric acid media. the reaction was followed spectrophotometrically at 478.5 nm (?max). under optimum experimental conditions, (72.6 ?mol l-1 of orange-g, 0.76 mol l-1 of h2so4, 0...

Journal: :Molecular pharmacology 2009
Aditi Pandya Martin Margaret A Park Clint Mitchell Teneille Walker Mohamed Rahmani Andrew Thorburn Dieter Häussinger Roland Reinehr Steven Grant Paul Dent

We examined whether the multikinase inhibitor sorafenib and histone deacetylase inhibitors (HDACI) interact to kill pancreatic carcinoma cells and determined the impact of inhibiting BCL-2 family function on sorafenib and HDACI lethality. The lethality of sorafenib was enhanced in pancreatic tumor cells in a synergistic fashion by pharmacologically achievable concentrations of the HDACIs vorino...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه صنعتی اصفهان 1390

section{introduction} the concept of {sl cartan geometry} appeared at the beginning of the twentieth century, when {e}lie cartan was working on the so-called {sl equivalence problem}, the aim of which is to determine whether two given geometric structures can be mapped bijectively onto each other by some diffeomorphism. this problem can be considered in many different contexts, such as ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تحصیلات تکمیلی علوم پایه زنجان - دانشکده فیزیک 1392

in the first part of this thesis we explored wetting and its dynamics for small droplets. first, we showed how a simple feature of water droplets on a surface, i.e. laplace pressure, can be exploited to build a micropump. we investigated capillary pumping in microchannels both experimentally and numerically. putting two droplets of different sizes at the in/outlet of a microchannel, will ge...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه رازی - دانشکده علوم 1388

abstract sensitive and precise voltammetric methods for the determination of trace amounts of furaldehydes, mainly as furfural (f) and 5-hydroxymethyl-2-furaldehyde (hmf), in waste waters and other matrices is described. determination of total furaldehyde at < ?g g-1 levels in alkaline buffered aqueous media was individually investigated. by the use of ordinary swv and adsorptive square wave ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تبریز - دانشکده علوم ریاضی 1387

فرض کنید g یک گروه متناهی باشد به طوری که مربع هر درجه کاراکتر تحویل ناپذیر آن اندیس مرکز گروه را عاد می کند. آیا می توان نتیجه گرفت که گروه پوچتوان یا حتی حلپذیر است؟ همچنین در مورد بعضی از تعمیمهای فوقالذکر بحث خواهیم کرد. همچنین، تا چه اندازه ساختار یک گروه حلپذیر توسط بزرگترین درجه کاراکتر تحویل ناپذیر گروه تحت تاثیر قرار میگیرد مورد بحث قرار خواهد گرفت. let g be a finite group such tha...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شیراز - دانشکده علوم 1388

چکیده : حاصل ضرب خارجی جزئی یک گروه g در مقابل حاصل ضرب خارجی s(g) توسط : نرجس فریدونی پایان نامه حاضر بر اساس مقاله partial crossed product of a group g vs crossed product of s(g) نگارش r . exel and f . vieira نوشته شده است. در این پژوهش تعریف تازه ای برای حاصل ضرب خارجی جزئی بوسیله عمل های نیم گروه های معکوس در یک c^*-جبر، بدون استفاده از نمایش هموردا که ناندور سایبن در ]15...

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