capacity was saturated by an acute intravenous infusion of iron, deposited a large fraction of intestinally absorbed iron in the liver during the first pass of portal venous blood through this organ.1 Subsequently, Wheby and Umpiere demonstrated similar results in normal human subjects given sufficient iron to acutely saturate their plasma iron-binding capacity.2 Our results in patients with sp...

A correlation has been established between the absorbed fraction of training-set molecules after oral administration in humans and the Quantum Mechanical Polar Surface Area (QMPSA). This correlation holds for the QMPSA calculated with structures where carboxyl groups are deprotonated. The correlation of the absorbed fraction and the QMPSA calculated on the neutral gas phase optimized structures...

The sensitivity to different relevant parameters of the absorbed fraction of alpha particles emitted from the 222Rn chain in sensitive cells of the tracheo-bronchial tree have been investigated. The structure of the airway wall given by ICRP (ICRP66) has been adopted and employed in the present calculations. The source thickness (mucous gel and sol + cilia), target layer thickness and the depth...

Novel lead oxide-based flexible dosimeters with superior performance were experimentally tested for electron therapy. However, absorbed/transmitted primary particle fraction and secondary radiation distribution from the dosimeter surface have not been reported. These features should be specified to improve dosimeter’s reliability medical applications. Hence, absorbed fraction, transmitted radia...

The internal dosimetry schema of the Medical Internal Radiation Dose (MIRD) Committee of the Society of Nuclear Medicine has provided a broad framework for assessment of the absorbed dose to whole organs, tissue subregions, voxelized tissue structures, and individual cellular compartments for use in both diagnostic and therapeutic nuclear medicine. The schema was originally published in 1968, r...

A model for bifurcation regions of the human tracheo-bronchial tree was developed. Equations for the surfaces are given to enable calculations of doses from alpha-particles emitted in these regions. It has been found that a bifurcation region is well approximated by a quasi-ellipsoid. The absorbed fractions of alpha-particles emitted in bifurcation regions were calculated by the Monte Carlo met...

Context. Aims. Intrinsic absorption is a fundamental physical property to understand the evolution of active galactic nuclei (AGN). Here a sample of 1290 AGN, selected in the 2–10 keV band from different flux-limited surveys with very high optical identification completeness is studied. Methods. The AGN are grouped into two classes, unabsorbed (type-1) and absorbed (type-2), depending on their ...