The canine parvovirus structure (CPV) [Tsao, Chapman, Agbandje, Keller, Smith, Wu, Luo, Smith, Rossmann, Compans & Parrish (1991). Science, 251, 1456-1464] has been refined by a real-space refinement procedure [Chapman (1994). Acta Cryst. A51, 69-801. The fit of an atomic model to electron density was optimized while taking into account the resolution limit of the data and the stereochemistry o...

The random K-satisfiability problem, consisting in verifying the existence of an assignment of N Boolean variables that satisfy a set of M5aN random logical clauses containing K variables each, is studied using the replica symmetric framework of diluted disordered systems. We present an exact iterative scheme for the replica symmetric functional order parameter together for the different cases ...

A51-year-old woman with breast cancer presented with progressive numbness and burning in the right lower gum and oral mucosa. Neurologic examination was normal except for reduced sensation in the right lower gum region. Inferior alveolar neuropathy from mandible metastasis was diagnosed (figures 1 and 2). “Numb chin syndrome” is characterized by decreased sensation in the chin or lower lip, ora...

A50 The emergence of G8P[8] rotavirus group A across Vietnam Pham Thanh Duy,* Tran Thi Ngoc Dung,* October M. Sessions, Maia A. Rabaa, Stephen Baker, The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam, Program in Emerging Infectious Diseases Duke-National University of Singapore Graduate Medical School...

Phenotypic variation of a single genotype is achieved by alterations in gene expression patterns. Regulation of such alterations depends on their time scale, where short-time adaptations differ from permanently established gene expression patterns maintained by epigenetic mechanisms. In the ciliate Paramecium, serotypes were described for an epigenetically controlled gene expression pattern of ...