The aim of the present study was to investigate the anticancer effect of quercetin (QC) in the human lung cancer cell line A-549 and further study the mechanism of apoptosis induction by QC. Low differentiation potential A-549 human lung cancer cells were treated with QC at different doses and for different times, and the growth inhibitory rates were detected by MTT assay. Apoptosis induced by ...

Software needs to be accessible for persons with disabilities and there are several guidelines to assist developers in building more accessible software. Regulation activities are beginning to make the accessibility of software a mandatory requirement in some countries. One such activity is the European Mandate M 376, which will result in a European standard (EN 301 549) defining functional acc...

We report the discovery of a kilohertz quasi–periodic oscillation (kHz QPO) in the low–mass X–ray binary (LMXB) 2S 0918–549. The kHz QPO has a frequency of 1156±9 Hz, a FWHM of 70±20 Hz, and a fractional rms amplitude of 18%±2%. We also detected for the first time a type I X–ray burst in this source. The compact object must therefore be a neutron star. Finally, we were able to classify the sour...

abstract cytotoxic effect of extract leaves of t. kotschyanus boiss. & hohen on human lang cell. t. kotschyanus boiss. & hohen was used in traditional medicine such as anti-inflammation, antispasmodic and gastrointestinal aim of this study was to survey the cytotoxic effects the of ethanol of leave of thymus kotschyanus on a-549 cell line. t. kotschyanus was collected on spring 2014 from selsel...

Galectin-3 (Gal-3), a member of the beta-galactoside binding protein family containing the NWGR antideath motif of the Bcl-2 protein family, is involved in various aspects of cancer progression. Previously, it has been shown that the antiapoptotic activity of Gal-3 is regulated by the phosphorylation at Ser(6) by casein kinase 1 (CK1). Here we questioned how phosphorylation at Ser(6) regulates ...

4 Xavier Bonnet, Alain Fizesan, Catherine Louise Michel 5 6 7 1. CEBC-CNRS, 79360 Villers en Bois, France 8 9 Correspondance : Xavier Bonnet ; Tel +33 549 097 879 ; Fax +33 549 096 111 ; email 10 [email protected] 11 12 13 Submitted for consideration in Journal of Experimental Biology 14 15 16

a Geo-resources Laboratory, associated Unit to CNRST (URAC42), Department of Earth Sciences, Faculty of Sciences and Technology Guéliz, Cadi Ayyad University, Abdelkarim Elkhattabi Avenue, Gueliz, P.O. Box 549, Marrakech, Morocco b Department of Geography, University of Ottawa, Ottawa (Ontario), Canada K1N 6N5 c HydrISE, Institut Polytechnique LaSalle Beauvais, 19 rue Pierre Waguet, F-60026 Bea...

Mycobacterium tuberculosis and M. avium complex strains given intramacrophage passage (I-type) were compared with those cultured in a liquid medium (E-type) for their drug susceptibilities when they were replicating in Mono-Mac-6 macrophages or A-549 cells. Their intracellular susceptibilities to rifalazil, clarithromycin, and levofloxacin were decreased more in I-type organisms than in E-type ...