objective(s): use of a positron emission tomography (pet)/single-photonemission computed tomography (spect) system facilitates the simultaneousacquisition of images with fluorine-18 fluorodeoxyglucose (18f-fdg) andtechnetium (99mtc)-tetrofosmin. however, 18f has a short half-life, and 511kev compton-scattered photons are detected in the 99mtc energy window.therefore, in this study, we aimed to ...

PURPOSE Myocardial fibrosis is considered to be an important factor in myocardial dysfunction and sudden cardiac death in hypertrophic cardiomyopathy (HCM). The purpose of this study was to compare myocardial fibrosis detected by late gadolinium enhancement (LGE) on cardiac MRI with myocardial perfusion and fatty acid metabolism assessed by single photon emission computed tomography in HCM. M...

UNLABELLED We assessed Takotsubo (ampulla) cardiomyopathy compared with acute coronary syndrome (ACS) using two-dimensional echocardiography and 99mTc-tetrofosmin myocardial SPECT. METHODS We examined 10 patients with Takotsubo cardiomyopathy and 16 with ACS at the time of emergency admission (acute phase), at three to nine days after the attack (subacute phase) and at one month after the att...

OBJECTIVES It has been postulated that radiopharmaceuticals can be used to predict the therapeutic response to (chemo)therapy, which could lead to individualized treatment regimens. In this study, 18F-deoxyglucose, 99mTc-tetrofosmin, 125I-deoxyuridineribose, and 125I-methyltyrosine were tested for this purpose. METHODS The uterine sarcoma cell line MES-SA (MDR-) and its multidrug resistant va...

Scintimammography is the functional imaging study of the breast with singlephoton radiopharmaceuticals, such as 99mTc-sestamibi or 99mTc-tetrofosmin. In 1994, Khalkhali et al. (1) reported the first series with a relatively large number of patients on the clinical application of scintimammography. In their group of 59 patients, in whom an abnormal mammogram and physical examination warranted bi...

UNLABELLED Obesity is a major heath problem associated with increased cardiovascular mortality. There are currently no data to support a role for stress imaging techniques in the risk stratification of obese patients. The aim of this study was to assess the independent value of stress 99mTc-tetrofosmin SPECT in predicting mortality and hard cardiac events in obese patients. METHODS We studied...

PURPOSE Despite recommendations for 99mTc-tetrofosmin dual tracer imaging for hyperparathyroidism in current guidelines, no report was published on dual-isotope 99mTc-tetrofosmin and 123I sodium iodide single-photon-emission-computed-tomography (SPECT). We evaluated diagnostic accuracy and the impact of preoperative SPECT on the surgical procedures and disease outcomes. METHODS Analysis of 70...

PURPOSE To use gated (G) 99mTc-Tetrofosmin single photon emission computed tomography (SPECT)-CT combined with coronary calcium (Ca) scores to assess and differentiate patients with left-sided breast cancer, after surgery and doxorubicin (DOX)-based chemotherapy and who had cardiac risk factors and needed to adapt radiotherapy (RT) in order to prevent cumulative cardiac side effects caused by R...