DEATH OF OLIGODENDROGLIAL PROGENITOR CELLS Makoto Horiuchi, Aki Itoh, David Pleasure and Takayuki Itoh From the Department of Neurology, University of California Davis, School of Medicine, Sacramento, California 95817, and the Institute for Pediatric Regenerative Medicine, Shriners Hospitals for Children Northern California, Sacramento, California 95817 Running title: Interferonand MEK-ERK sign...

I. History and Discovery 904 A. Calcitonin gene-related peptide: a novel neuropeptide 904 B. Adrenomedullin: a tissue-derived peptide 905 C. Amylin: a pancreatic peptide 905 II. Structure 905 III. Distribution and Regulation of Genes and Peptides 906 A. CGRP: a wide distribution 906 B. AM: upregulation in disease 907 C. Amylin: relevance to diabetes 908 IV. Receptors 908 A. Cloning of CGRP rece...

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Three families of Bacillus cyclic lipopeptides--surfactins, iturins, and fengycins--have well-recognized potential uses in biotechnology and biopharmaceutical applications. This study outlines the isolation and characterization of locillomycins, a novel family of cyclic lipopeptides produced by Bacillus subtilis 916. Elucidation of the locillomycin structure revealed several molecular features ...

I. History and Discovery 904 A. Calcitonin gene-related peptide: a novel neuropeptide 904 B. Adrenomedullin: a tissue-derived peptide 905 C. Amylin: a pancreatic peptide 905 II. Structure 905 III. Distribution and Regulation of Genes and Peptides 906 A. CGRP: a wide distribution 906 B. AM: upregulation in disease 907 C. Amylin: relevance to diabetes 908 IV. Receptors 908 A. Cloning of CGRP rece...

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The roles of purified Int and Xis proteins of the conjugative transposon Tn 916 in excision of a deletion derivative of the closely related element Tn 1545 were investigated. At a low salt concentration (37.5 mM NaCl), Int alone was able to promote limited excision to produce a covalently closed circular form of the transposon, showing that Tn 916 Int can catalyze both DNA cleavage and strand e...

Lei Wang, Zheng Gang Zhang, Sara R. Gregg, Rui Lan Zhang, Zhongxian Jiao, Yvonne LeTourneau, Xianshuang Liu, Yifan Feng, Jens Gerwien, Lars Torup, Marcel Leist, Constance Tom Noguchi, Zhi-Yong Chen, Michael Chopp Departments of Neurology, Henry Ford Health Sciences Center, 2799 W. Grand Boulevard, Detroit, Michigan 48202; Department of Physics, Oakland University, Rochester, Michigan 48309; Dru...

Atrial natriuretic peptide receptor A (NPRA) plays important role(s) in the control of extracellular fluid volume and blood pressure homeostasis. We have determined and analyzed the functional promoter region of Npr1 gene (coding for NPRA) and studied the effect of angiotensin (Ang) II on its promoter activity and expression in cultured mouse mesangial cells. The promoter analysis of Npr1 gene ...