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Newly synthesized rifamycin derivatives, KRM-1648, KRM-1657, KRM-1668, KRM-1686, and KRM-1687, having the chemical structures of 3'-hydroxy-5'-(4-alkylpiperazinyl)-benzoxazinorifamycins (alkyl residues: isobutyl, propyl, sec-butyl, sec-butyl [R configuration], and sec-butyl [S configuration], respectively), were studied for their in vitro antimycobacterial activities. Representative (KRM-1648) ...
in order to comprise the effects of sodium bicarbonate supplementation on anaerobic performance and some plasma metabolites, 16 young male athletes (age 20.58?3.25, height 175.33?2.48 cm and bmi 21.57? 2.68 kg/m2) participated in two 400 m running sessions one hour following sodium bicarbonate or placebo (calcium bicarbonate) supplementation with the counterbalanced order. there were three bloo...
BACKGROUND The role of pulmonary hypertension as a cause of mortality in sickle cell disease (SCD) is controversial. METHODS AND RESULTS We evaluated the relationship between an elevated estimated pulmonary artery systolic pressure and mortality in patients with SCD. We followed patients from the walk-PHaSST screening cohort for a median of 29 months. A tricuspid regurgitation velocity (TRV)≥...
Bipolar electrograms were recorded from five to six sites on the septal right bundle branch (RBB) using a multielectrode patch in ten mongrel dogs. Antegrade activation was recorded along the right bundle during sinus rhythm and during right atrial pacing at varying heart rates. Retrograde activation was produced by pacing from right ventricular epicardium. Right bundle conduction velocities va...
This paper aims in the construction of an Artificial Neural Network model that performs successful estimation of the Maximum Water Supply (m /sec) and of the Special Water Flow (m/sec*Km) using several topographic, meteorological and morphometric parameters as independent variables. Support Vector Machines applying specific Kernel algorithms [9] are used to determine the Error or Loss of the Ne...
Contrast-enhanced ultrasonography (CEUS) of the hepatic vein can assess intrahepatic hemodynamic changes and has been studied as a noninvasive method to assess the severity of portal hypertension and hepatic fibrosis in humans. However, few reports have described its usefulness in veterinary medicine. The purpose of this study was to characterize CEUS findings of the hepatic vein in normal dogs...
Respiratory modulated neurons of the rabbit were examined for efferent projections and afferent connections via the spinal cord or the vagal nerves. Variability of latency of responses proved to be related to latencies. When latency of evoked potentials is plotted versus variability of latency, monosynaptic responses can apparently be discriminated from oligo- or polysynaptic responses. Latency...
Nomenclature H AW adiabatic wall enthalpy (J/kg) H w wall enthalpy (J/kg) H 0 total enthalpy (J/kg) h heat transfer coefficient (kg/m 2 /sec), h FR reference Fay-Riddell heat transfer coefficient (kg/m 2 /sec) L model reference length (m) M ∞ free stream Mach number q FR reference Fay-Riddell heat transfer rate (W/m 2) Re ∞ free stream unit Reynolds number (1/m) T ∞ free stream temperature (K) ...
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