We have designed and synthesized two radioiodinated analogs of hexadecylphosphocholine in order to evaluate their tumor imaging potential. 12-(m[125I]iodophenyl)dodecyl phosphocholine (NM-324) and hexadecyl-2-[N,N-dimethyl-N-(m[125I]iodobenzyl)-ammonium] ethyl phosphate (NM-326) demonstrated the ability of such compounds to localize in and thereby visualize the Walker 256 tumor in rats. However...

Hollow spherical gold nanoparticle superstructures with tunable diameters (∼40 nm, ∼70 nm and ∼150 nm) and visible to near-infrared surface plasmon resonances (545 nm, 670 nm, and 740 nm) are prepared using a single peptide conjugate, C6-AA-PEPAu, as the structure-directing agent. Computational models are developed to understand their optical properties.

High electron mobility transistors (HEMTs) based on III–V semiconductor materials have been investigated as these devices are scaled down to gate lengths of 120, 90, 70, 50 and 30 nm. A standard Monte Carlo (MC) method coupled with the solution of Poisson’s equation is employed to simulate a particle transport. The average particle velocity and the field–momentum relaxation time are studied in ...

For many thin-film applications substrate imperfections such as particles, pits, scratches, and general roughness, can nucleate film defects which can severely detract from the coating's performance. Previously we developed a coat-and-etch process, termed the ion beam thin film planarization process, to planarize substrate particles up to approximately 70 nm in diameter. The process relied on n...

We demonstrate the fabrication of poly(3,4-ethylenedioxythiophene) poly(styrenesulfonate) (PEDOT:PSS) nanogratings by a dehydration-assisted nanoimprint lithographic technique. Dehydration of PEDOT:PSS increases its cohesion to protect the nanostructures formed by nanoimprinting during demolding, resulting in the formation of high quality nanogratings of 60 nm in height, 70 nm in width and 70 n...

AIM To evaluate the effects of small interference RNA protein kinase C-alpha (siRNA-PKCα) on experimental proliferative vitreoretinopathy (PVR) induced by dispase in mice. METHODS C57BL/6 mice PVR models (4-6 weeks old) were induced by intravitreal injection of dispase and then equally divided into six groups. After 1 week, the five treatment groups received 2 μL, intravitreal injections of s...

The combination of gold and copper is a good way to pull down the cost of gold and ameliorate the instability of copper. Through shape control, the synergy of these two metals can be better exploited. Here, we report an aqueous phase route to the synthesis of pentacle gold-copper alloy nanocrystals with fivefold twinning, the size of which can be tuned in the range from 45 to 200 nm. The growth...

We demonstrate, for the first time, a silica-based fiber Bragg grating (FBG) with a wavelength tuning range over 70 nm, using compressive bending given by a simple tuning package. The wide tuning range of the device (from 1614 nm to 1544 nm), covers the entire Lband and a half of the C-band. Its polarization-mode dispersion (PMD) and polarization-dependent loss (PDL) remain low over the full op...