نتایج جستجو برای: 7 hydroxy coumarin

تعداد نتایج: 672373  

Journal: :Journal of the Korean Chemical Society 2012

2010
Sreekanth Reddy

Coumarins are a class of compounds with benzopyrone ring system. In the present work 7-hydroxy-4-methyl coumarin was prepared by the reaction of resorcinol and ethylacetoacetate mixture in the presence of concentrated sulphuric acid. 7-hydroxy-4-methyl coumarin was acetylated with acetic anhydride in the presence of acetic acid. The product formed was treated with bromine in glacial acetic acid...

Journal: :Physical chemistry chemical physics : PCCP 2013
Caroline M Krauter Jens Möhring Tiago Buckup Markus Pernpointner Marcus Motzkus

In the present work we have explored the ultrafast relaxation network of coumarin and umbelliferone (7-hydroxy-coumarin) using time-resolved femtosecond spectroscopy and quantum chemical calculations. Despite the importance of the photophysical properties of coumarin derivatives for applications in biomedicine, the low fluorescence quantum yield of coumarin itself has not been fully understood ...

Journal: :Chemical communications 2012
Zhisheng Wu Zhu Li Liu Yang Jiahuai Han Shoufa Han

Selective detection of hydrogen sulfide was achieved with 7-o-2'-(azidomethyl)benzoyl-4-methylcoumarin via analyte mediated reductive removal of the 2'-(azidomethyl)benzoyl moiety and concurrent generation of fluorescent 7-hydroxy-4-methylcoumarin.

Journal: :Archives of pharmacal research 2003
Ashraf Taha Khalil Fang-Rong Chang Yue-Han Lee Chung-Yi Chen Chih-Chuang Liaw Patnam Ramesh Shyng-Shiou F Yuan Yang-Chang Wu

Two quinazolone alkaloids, (+)-febrifugine (1) and isofebrifugine (2), along with three coumarin derivatives, 6-hydroxy coumarin (3), skimmin (5), and umbelliferone-7-O-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranoside (6), were isolated from the roots of Hydrangea chinensis. Compound 6 is a new compound. In addition, umbelliferone (4), linoleic acid (7), two steroidal glycosides (8, 9), th...

Journal: :Antiviral chemistry & chemotherapy 2002
Dale L Barnard Z e Q i Xu Valerie D Stowell Hongwei Yuan Donald F Smee Raghu Samy Robert W Sidwell M Kim Nielsen Lihui Sun Hua Cao Ailing Li Clay Quint Jeffrey Deignan Jennifer Crabb Michael T Flavin

A series of coumarin and pyranocoumarin analogues were evaluated in vitro for antiviral efficacy against measles virus (MV), strain Chicago. Of the 22 compounds tested for inhibition, six were found to have selectivity indices greater than 10. These were compounds 5-hydroxy-7-propionyloxy-4-propylcoumarin (2a), 5,7-bis(tosyloxy)-4-propylcoumarin (7); 5-hydroxy-4-propyl-7-tosyloxy-coumarin (8); ...

Journal: :Acta pharmaceutica 2004
Vinod Kumar Pandey Sarah Tusi Zehra Tusi Madhawanand Joshi Shashikala Bajpai

Reaction of 7-hydroxy-4-methyl coumarin with amido/ imido alcohols in ethanol containing concentrated hydrochloric acid afforded 8-aralkyl amido/imido-alkyl-7-hydroxy-4-methyl-coumarins (1a-f). Interaction of 1a-f with hydrazine hydrate in pyridine resulted in 1-amino-8-aralkyl amido/imido-alkyl-7-hydroxy-4-methyl-2-oxo-quinolines (2a-f). Treatment of 2 with formaldehyde in ethanol resulted in ...

Journal: :Heterocyclic Communications 2022

Abstract Many coumarin derivatives have good biological activity and application value in fluorescent probes. Therefore, synthetic routes to also attracted the attention of many research groups. In this work, based on Pechmann synthesis method, influence various Lewis acids reaction was discussed, optimal conditions 7-hydroxy-4-substituted coumarins were explored. Based experimental results, a ...

Journal: :Chemistry 2016
Shamil Nizamov Maksim V Sednev Mariano L Bossi Elke Hebisch Holm Frauendorf Stephan E Lehnart Vladimir N Belov Stefan W Hell

Large Stokes-shift coumarin dyes with an O-phosphorylated 4-(hydroxymethyl)-2,2-dimethyl-1,2,3,4-tetrahydroquinoline fragment emitting in the blue, green, and red regions of the visible spectrum were synthesized. For this purpose, N-substituted and O-protected 1,2-dihydro-7-hydroxy-2,2,4-trimethylquinoline was oxidized with SeO2 to the corresponding α,β-unsaturated aldehyde and then reduced wit...

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