The inhibitor constants of several inhibitors for cyclic AMP- and cyclic GMP-phosphodiesterase from various organs are compared. The inhibitors were classical theophyline, papaverine, and some of newly developed inhibitors: an imidazolidinone compound, RO20-1724, and two phthalazinol compounds, EG 467 and EG 626. Among the inhibitors tested, papaverine and EG 626 were found to be the most poten...

The homily on the Avar siege of Constantinople in 626 attributed to Theodore Syncellus shares numerous linguistic features both with Theodore’s 623 Virgin’s Robe and George Pisidia’s poem 626/7 siege. celebrate combined efforts Patriarch Sergius Virgin Mary saving city, but also highlights involvement other agents, particular patrician Bonus young Heraclius Constantine, who were jointly charge ...

Trastuzumab is a growth-inhibitory humanized Ab targeting the oncogenic protein HER-2/neu. Although trastuzumab is approved for treatment of advanced breast cancer, a number of concerns exist with passive immunotherapy. Treatment is expensive and has a limited duration of action, necessitating repeated administrations of the mAb. Active immunotherapy with conformational B cell epitopes affords ...

We calculate e+e− → t̃1t̃1Z at a linear collider. For large splitting between the two stops the cross-section is sensitive to the value of mt̃2 when this particle is too heavy to be directly produced. The results are compared to e+e− → t̃1t̃1h LAPTH-740/99 KEK-CP-086/99 AP-SU-99/02 June 1999

A subclass of dynamical semigroups induced by the interaction of a quantum system with an environment is introduced. Such semigroups lead to the selection of a stable subalgebra of effective observables. The structure of this subalgebra is completely determined. ∗Supported by the KBN research grant No 2 P03B 086 16