−The purpose of this investigation was to enhance the dissolution rate of loratadine using polyethylene glycol 6000 (PEG) solid dispersions (SDs). The solubility behavior of loratadine in the presence of polyethylene glycol 4000 and polyethylene glycol 6000 in water showed linear increase with increasing concentrations of PEG, indicating AL type solubility diagrams. SDs of loratadine with PEG 6...

We propose a new method to detect the gravitational lenses in the ongoing microlensing experiments using medium and high resolution spectroscopy (λ/∆λ > 6000). Since the radial velocity of the lens and lensed source typically differs by ∼ 100 km s−1, the spectral lines from the lens and source will be shifted relative to each other by (1− 2)Å in the optical. We simulate realistic composite spec...

OBJECTIVE To determine the reliability of the Cybex 6000 isokinetic dynamometer in measuring the knee muscle performance concentrically and eccentrically. METHODS 18 male and 12 female subjects with no previous knee injuries, who had not previously undergone any isokinetic testing, were studied. The flexor and extensor muscles groups of both knees were tested at 60 degrees s-1 and 120 degrees...

Pharmaceutical availability of diazepam, oxazepam and nitrazepam from solid dispersions of PEG 6000 have been studied in comparison with corresponding physical mixtures and pure benzodiazepines. Selected derivatives of 1,4-benzodiazepin-2-one are poorly water soluble drugs. The aim of this work was to report the properties of diazepamand nitrazepam-PEG 6000 solid dispersions. Differential scann...

Pharmaceutical aviailability of diclofenac sodium from solid dispersions of PEG 6000 have been studied in comparison to those of the corresponding physical mixtures and pure diclofenac sodium. The diclofenac sodium is poorly water soluble drug. The properties of diclofenac sodium-PEG 6000 solid dispersions have been determined by the methods of differential scanning calorimetry (DSC), X-ray dif...

This note describes a performance evaluation of a workstation based on the Silicon Graphics R8000 microprocessor running at 75 MHz. The evaluation is based on a variety of Fortran77 benchmark codes that have a range of computational characteristics and that represent Los Alamos National Laboratory applications. Benchmark data from the R8000 system are compared with those from an IBM RISC System...

Shape memory polyurethanes (SMPUs) are typically synthesized using polyols of low molecular weight (MW~2,000 g/mol) as it is believed that the high density of cross-links in these low molecular weight polyols are essential for high mechanical strength and good shape memory effect. In this study, polyethylene glycol (PEG-6000) with MW ~6000 g/mol as the soft segment and diisocyanate as the hard ...

John Hilton Edwards [7] first described the symptoms of the genetic disorder known as Trisomy 18?one of the most common forms of human trisomy, which occurs when cells have an extra copy of a chromosome, in 1960. Trisomy 18 [5], also known as Edwards Syndrome [6], occurs approximately once per 6000 live births and is second in frequency only to Trisomy 21, or Down?s Syndrome, as an autosomal tr...

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