BackgroundTarget-controlled infusion (TCI) systems incorporating pharmacokinetic (PK) or PK-pharmacodynamic (PK-PD) models can be used to facilitate drug administration. Existing were developed using data from select populations, the use of which is, strictly speaking, limited these populations. Recently a propofol PK-PD model was for broad population range. The aim study prospectively validate...

Infection with Helicobacter pylori (formerly Campylobacter pylori) was studied by measuring antibody titres to H pylori in Gambian children. Serological evidence of infection was found in 12 of 82 (15%) infants aged less than 20 months; this increased to 62 of 135 (46%) in those aged 40-60 months. Positive serology was found in 41 of 77 (53%) infants with chronic diarrhoea and malnutrition (mea...

BACKGROUND The aim of this study was to evaluate the efficacy of a proportional derivative algorithm closed-loop system to control postprandial glucose concentrations in subjects with type 1 diabetes. METHODS Six subjects treated with continuous subcutaneous insulin infusion received a standardized meal on three days. The first day served as control, the second day as learning experiment for ...

OBJECTIVE To investigate the andropause phenomenon in Iraqi healthy subjects by evaluating serum free testosterone (FT) concentrations in association with age. METHODS This study was carried out at the Biochemistry Department, College of Medicine, University of Baghdad, between February 2012 and October 2012. This cross sectional control subject's study included 251 healthy Iraqi men with an ...

OBJECTIVE To identify age-related changes in human meibomian glands that may be associated with meibomian gland dysfunction (MGD). METHODS Excess eyelid tissue from 36 patients (age range, 18-95 years, 19 female, 17 male) who underwent canthoplasty procedures were used. Dermatologic history, age, and presence of MGD were recorded. Samples were frozen, sectioned, and stained with specific anti...