BACKGROUND The EQ-5D is a brief, generic measure of health status that can be easily incorporated into population health surveys. There are two versions of the EQ-5D for use in adult populations, one with 3 response levels in each of the instrument's 5 dimensions (EQ-5D-3L) and one with 5 levels in each dimension (EQ-5D-5L). We compared the two versions as measures of self-reported health statu...

5d, a novel analogue of the racemic 3-n-butylphthalide (NBP), has been reported for its free radical scavenging activity in vitro and preventive neuroprotection in vivo. Nevertheless, the mechanism by which 5d attenuated ischemia/reperfusion (I/R) injury is still unknown. Our results showed that 5d significantly increased CK2 activity as well as CK2α and 2α' protein levels after I/R injury. Bes...

OBJECTIVE To investigate the construct and criterion validity of the Euro Qol-5D (EQ-5D), which allows quality-adjusted life-years to be calculated, in patients with systemic lupus erythematosus (SLE). METHODS Consecutive SLE patients who had been followed at the Renji Hospital, School of Medicine, Shanghai Jiao Tong University were recruited. Cross-sectional correlations of the EQ-5D with eq...

In the context of theories of Kaluza-Klein type, with a large extra dimension, we study self-similar cosmological models in 5D that are homogeneous, anisotropic and spatially flat. The “ladder” to go between the physics in 5D and 4D is provided by Campbell-Maagard’s embedding theorems. We show that the 5-dimensional field equations RAB = 0 determine the form of the similarity variable. There ar...

BACKGROUND The EQ-5D is a generic questionnaire providing a preference-based index score applicable to cost-utility analysis. This is the first study to validate the EQ-5D in patients with somatoform disorders. METHODS Data of the EQ-5D descriptive system, the British and the German EQ-5D index and the EQ Visual Analogue Scale, the Patient Health Questionnaire 15, the Patient Health Questionn...

BACKGROUND CONTEXT Clinimetric properties of the EuroQol-5D (EQ-5D) in patients with nonspecific chronic low back pain (CLBP) are largely unknown. PURPOSE To study the criterion validity, responsiveness, and minimal clinically important change (MCIC) of EQ-5D in patients with CLBP. STUDY DESIGN Prospective study design carried out in a multispecialist Spine Center in The Netherlands. PATI...

BACKGROUND The EQ-5D is a generic questionnaire which generates a health profile as well as index scores for health-related quality of life that may be used in cost-utility analysis. AIMS OF THE STUDY To examine validity and responsiveness of the EQ-5D in patients with anxiety disorders. METHODS 389 patients with anxiety disorders completed the EQ-5D at baseline and 6-month follow-up. Subje...

BACKGROUND The EuroQoL 5D (EQ-5D) has been widely used in studies of cardiac disease, but its measurement properties in this group are not well established. The study aimed to quantify the relationship between measures commonly used in studies of cardiac disease and the EQ-5D index across different levels of disease severity. METHODS Patient-level data from 7 studies of cardiac interventions ...

BACKGROUND AND OBJECTIVE It is well established that there are problems with the EQ-5D. This is due to the original scoring methods used and how negative time trade-off (TTO) values were treated. A revised scoring method has been published. This article applies this to an inflammatory arthritis cohort. The objective is to examine the impact of a revised scoring system for the EQ-5D (UK) TTO on ...

We consider a five dimensional (5D) space-time with a space-like fifth dimension. We implement a quantum formalism by path integrals, and postulate that all the physical information on a 5D massless particle propagation is provided by the statistics over null paths in this 5D space-time. If the 5D metric is independent of the fifth coordinate, then the propagation problem can be reduced to four...