QUESTION Is there a difference in the level and pattern of free-living physical activity between individuals with chronic low back pain and matched controls? DESIGN Observational, cross-sectional study. PARTICIPANTS Fifteen individuals with chronic low back pain and fifteen healthy controls matched for age, gender, and occupation. OUTCOME MEASURES Participants wore an activity monitor for...

Introduction: The alteration in serum lipid profile; increase in total cholesterol (TC), triacylglycerol (TAG), and low-density lipoprotein cholesterol (LDL-C); and reduction in high-density lipoprotein cholesterol (HDL-C) are key factors in cardiovascular disease progression. The high prevalence and severity of cardiovascular diseases require new screening tools for better evaluation. Atheroge...

Understanding the relationships between regulatory factor binding, chromatin structure, cis-regulatory elements and RNA-regulation mechanisms relies on accurate information about transcription start sites (TSS) and polyadenylation sites (PAS). Although several approaches have identified transcript ends in yeast, limitations of resolution and coverage have remained, and definitive identification...

BACKGROUND There has been a major and alarming increase in readmission rates following total joint arthroplasty. With proposed changes in reimbursement policy, increased rates of unplanned readmission following arthroplasty will penalize providers. In particular, it has been proposed that specific complications--so-called "zero-tolerance" complications--are unacceptable and that their treatment...

We extend the immersed boundary (IB) method to simulate the dynamics of a 2D dry foam by including the topological changes of the bubble network. In the article [Y. Kim, M.-C. Lai, and C. S. Peskin, J. Comput. Phys. 229:5194-5207, 2010], we implemented an IB method for the foam problem in the two-dimensional case, and tested it by verifying the von Neumann relation which governs the coarsening ...