The promising antiviral properties of 3'-fluoro-3'-deoxyadenosine and 4',4'-difluoro-4'-deoxy-5'-noraristeromycin prompted the synthesis of the corresponding 3'-fluoro derivatives of 5'-noraristeromycin. These target compounds, which were prepared from the same readily accessible cyclopentenol, were found to be inactive when subjected to 31 viral assays. The results have some implications on th...

an efficient method has been developed for the catalysis of condensation of 1,2-phenylenediamines and 2-aminothiophenoles with different aldehydes into their corresponding 2-aryl-1h-benzimidazoles and 2-aryl-1h-benzothiazoles under mild condition. in this method, trans-3,5-dihydroperoxy-3,5-dimethyl-1,2-dioxolane (dhpdmdo)/hoac/ki system was used as a novel and effective oxidant in water at roo...