AIMS Patients with diabetes mellitus have more extensive coronary artery disease, more disease progression, and restenosis. The use of drug-eluting stents (DES) in these patients is widespread, despite uncertain long-term safety and efficacy. METHODS AND RESULTS All consecutive patients with diabetes mellitus in Sweden who underwent percutaneous coronary intervention were entered into the Swe...

BACKGROUND Partial nephrectomy (PN) may better protect against other-cause mortality (OCM) when compared with radical nephrectomy (RN) in patients with localized renal cell carcinoma (RCC). OBJECTIVE Test the effect of treatment type on OCM. DESIGN, SETTING, AND PARTICIPANTS Using the Surveillance Epidemiology and End Results-Medicare-linked database, 4956 RN patients (82%) and 1068 PN pati...

Background & Aims: Age-related macular degeneration (ARMD) is one of the common retina disorders that can lead to loss of vision by increase in age. In this study, the efficacy of a non-invasive ultrasound technique for the evaluation of alastic properties of eye in the diagnosis of ARMD has been evaluated. Methods: For estimation of the elastic modulus of eye, spatial loading system designed a...

components : (a) the extracellular fluids, which include blood, interstitial fluid, and lymph (if existing in the tumor) ; and (b) the extracellular solids, consisting mainly of connective tissue proteins and mucopolysaccharides of the ground and cement substances. The components of the extracellular compartment are arranged in a structure which can be described morphologically as a frame of co...

The thesis is based on the following publications: 1. Ejlertsen B, Jensen MB, Mouridsen HT. Excess mortality in postmenopausal women who only receive adjuvant endocrine therapy for estrogen receptor positive breast cancer. Acta Oncol 2014;53:174-85. 2. Ejlertsen B, Jensen MB, Elversang J, Rasmussen BB, Andersson M, Andersen J, Nielsen DL, Cold S, Mouridsen HT. One year of adjuvant tamoxifen com...

Petroleum and dairy operations are prominent sources of gas-phase organic compounds in California’s San Joaquin Valley. It is essential to understand the emissions and air quality impacts of these relatively understudied sources, especially for oil/gas operations in light of increasing US production. Ground site measurements in Bakersfield and regional aircraft measurements of reactive gas-phas...

Cytochromes P450 (CYP, phase I) and conjugating (phase II) enzymes can be induced by and influence the toxicokinetics (metabolism) and toxicity of xenobiotic contaminants in exposed organisms. Beluga whale (Delphinapterus leucas) from the endangered St. Lawrence (SL) River Estuary population exhibit deleterious health effects and various severe pathologies that have been associated with contami...