PURPOSE The aim of this study is to know whether silibinin has an anticancer effect on triple negative breast cancer xenograft model using MDA-MB-468 cells. METHODS To establish the xenograft model, we injected the MDA-MB-468 cells into female Balb/c-nude mice. After establishing a xenograft model, oral silibinin was administered to the tested mice in the way of 200 mg/kg for 45 days. The dif...

CXC ligand (L)12 is a chemokine implicated in the migration, invasion and metastasis of cancer cells via interaction with its receptors CXC chemokine receptor (CXCR)4 and CXCR7. In the present study, CXCL12-mediated Ca2+ signalling was compared with two basal-like breast cancer cell lines, MDA-MB-231 and MDA-MB-468, which demonstrate distinct metastatic potential. CXCL12 treatment induced Ca2+ ...

Yasuhiko Miyazaki Nippon Telegraph and Telephone Corp. Human Interface Laboratories Room 509A, 1-1 Hikarino-oka Yokosuka, 239, Japan Phone +81-468-59-4067 Fax +81-468-55-1730 [email protected] Klara Nahrstedt University of Illinois at Urbana-Champaign Department of Computer Science 1304 W. Springfield Ave. Urbana, Illinois, 61801, USA Phone 1-217-244-6624 Fax 1-217-244-6869 klara@cs....

To further understand the emergence of serotype IV group B Streptococcus (GBS) invasive disease, we used whole-genome sequencing to characterize 3 sequence type 468 strains isolated from neonates in Minnesota, USA. We found that strains of tetracycline-resistant sequence type 468 GBS have acquired virulence genes from a putative clonal complex 17 GBS donor by recombination.

The specificity of a novel epidermal growth factor (EGF)-Cy5.5 fluorescent optical probe in the detection of EGF receptor (EGFr) was assessed using continuous-wave fluorescence imaging accomplished via an intensified charge-coupled device (CCD) camera. Human mammary MDA-MB-468 (EGFr+) and MDA-MB-435 (EGFr-) cancer cells were incubated with Cy5.5, EGF-Cy5.5, or the anti-EGFr monoclonal antibody ...

previous studies have indicated that some species of cuscuta possess anticancer activity on various cell lines. due to the lack of detailed researches on the cytotoxic effects of cuscuta chinensis and cuscuta epithymum , the aim of the present study was to evaluate cytotoxic effects of chloroform and hydroalcoholic extracts of these plants on the human breast carcinoma cell line (mda-mb-468), h...

A variety of approaches have been studied in the past to overcome the problems encountered with the delivery of antifungal, for effective treating of oral and vaginal candidiasis. In this study, a novel mucoadhesive tablets with pH-independent drug release characteristic was prepared by chitosan and carbopol® 71G interpolymer complex (IPC) claims for multipurpose use. Precipitation method is em...

In Lecture 4, we learned about an algebraic method for describing and classifying structures. In this lecture, we look at using algebra to find combinatorial descriptions of topological spaces. We begin by looking at an equivalence relation called homotopy that gives a classification of spaces that is coarser that homeomorphism, but respects the finer classification. That is, two spaces that ha...

468 Urticarial Vasculitis After Bee-sting Therapy June-Hyuk Lee, Sung Woo Park, An-Soo Jang, DoJin Kim, and ChoonSik Park. Respiratory and allergy, Soonchunhyang University Bucheon Hospital, Bucheon, South Korea; Division of Respiratory and Allergy Medicine, Soonchunhyang University Hospital, College of Medicine, Bucheon, South Korea. Background: Bee-sting therapy is one of the oriental traditi...