Ideally, bioactive ceramics for use in alveolar ridge augmentation should possess the ability to activate bone formation and, thus, cause the differentiation of osteoprogenitor cells into osteoblasts at their surfaces. Therefore, in order to evaluate the osteogenic potential of novel bone substitute materials, it is important to examine their effect on osteoblastic differentiation. This study e...

Air abrasion as a caries removal technique is less aggressive than conventional techniques and is compatible for use with adhesive restorative materials. Alumina, while being currently the most common abrasive used for cutting, has controversial health and safety issues and no remineralisation properties. The alternative, a bioactive glass, 45S5, has the advantage of promoting hard tissue remin...

Bioglass 45S5 is a bioactive glass that can create a layer of calcium-phosphate crystals on mineralized hard tissues. In this study, 45S5 bioglass was mixed with phosphoric acid and irradiated with CO2 laser and examined as a possible aid in the treatment of dentin hypersensitivity. The dentinal surface modified by the aforementioned technique was chemically and micro-morphologically examined w...

As also observed for conventional silicate glasses, water can be incorporated in the bulk interstitial regions of a bioactive glass (BG) matrix during the glass preparation and/or upon exposure to an aqueous environment. However, in the case of BGs, very little is known about the effect of hydration on the bulk structure, and then on key properties of these materials, such as biodegradation and...

Molecular dynamics simulations of Na(+)/H(+)-exchanged 45S5 Bioglass® models reveal that a large fraction of the hydroxyl groups introduced into the proton-exchanged, hydrated glass structure do not initially form covalent bonds with Si and P network formers but remain free and stabilised by the modifier metal cations, whereas substantial Si-OH and P-OH bonding is observed only at higher Na(+)/...

In this study, the fabrication and properties of a synthetic keratoprosthesis skirt for use in osteo-odonto-keratoprosthesis (OOKP) surgery are discussed. In the search for a new material concept, bioactive glass and polymethyl methacrylate (PMMA)-based composites were prepared. Three different bioactive glasses (i.e. 45S5, S53P4 and 1-98) and one slowly resorbing glass, FL107, with two differe...

OBJECTIVES The aim of the present study was to test cutting efficiency of different materials against conventional alumina in an air abrasion system. MATERIALS AND METHODS The powder samples were divided into three groups: Group 1 - alumina (control), Group 2 - 45S5 bioactive glass, and Group 3 - hydroxyapatite. 30 microscope glass slides of 0.5 mm thickness were used as an alternative of hum...

Tissue engineering is a multi-disciplinary field, which aims to apply innovative biomaterials to replace or restore ill or damaged tissues of the human body, such as skin and bones. In particular, porous scaffolds are used as temporary 3D templates to support cell attachment and proliferation during the spontaneous regeneration of natural tissues and this approach is particularly promising for ...