Direction discrimination thresholds for maximum motion displacement (D(max)) have been previously reported to be abnormal in amblyopic children [Ho, C. S., Giaschi, D. E., Boden, C., Dougherty, R., Cline, R., & Lyons, C. (2005). Deficient motion perception in the fellow eye of amblyopic children. Vision Research, 45, 1615-1627; Ho, C. S., & Giaschi, D. E. (2006). Deficient maximum motion displa...

Fatigue is a common complaint among older adults. Evidence grows that fatigue linked to several negative health outcomes. A general overview of and its relationship with outcomes still lacks in the existing literature. This brings complications for healthcare professionals researchers identify fatigue-related risks. Therefore, this study gives an prospective predictive value main community-dwel...

Abstract Background Randomized controlled trials (RCTs) comparing percutaneous coronary intervention (PCI) with drug-eluting stents and artery bypass grafting (CABG) for patients left main disease (LMCAD) have reported conflicting results. Objectives We performed a systematic review from inception to 23 May 2021 one-stage reconstructed individual-patient data meta-analysis (IPDMA) that included...

BACKGROUND Despite several clinical studies, efficacy of coronary artery bypass grafting (CABG) surgery versus percutaneous coronary intervention (PCI) in patients with left main (LM) disease remains controversial. The objective of this meta-analysis of randomized trials was to evaluate the clinical outcome of CABG versus PCI with drug-eluting stents in LM coronary disease. METHODS We systema...

BACKGROUND Blood-based proteomic profiling may aid and expand our understanding of diseases and their different phenotypes. The aim of the presented study was to profile serum samples from patients with malignant melanoma using affinity proteomic assays to describe proteins in the blood stream that are associated to stage or recurrence of melanoma. MATERIAL AND METHODS Multiplexed protein ana...

OBJECTIVE We conducted a descriptive study of symptomatic epilepsy by age at onset in a cohort of patients who were followed up at a neuropaediatric department of a reference hospital over a 3-year period PATIENTS AND METHODS: We included all children with epilepsy who were followed up from January 1, 2008 to December 31, 2010 RESULTS: Of the 4595 children seen during the study period, 605 (13....

Abstract Background The incidence of oesophageal cancer has been steadily increasing over the past 30 years in many countries. UK highest adenocarcinoma world which is associated with obesity and gastro-oesophageal reflux disease. study aimed to determine trends England between 1985-2017. Methods Individual-level data for patients diagnosed were obtained from Office National Statistics/Public H...

OBJECTIVES To compare the safety and efficacy of percutaneous coronary intervention (PCI) using drug-eluting stent (DES) and coronary artery bypass graft (CABG) for the treatment of left main coronary artery (LMCA) disease. BACKGROUND Several new randomized trials have recently examined the clinical outcomes of PCI and CABG in LMCA disease. However, the results of these studies were inconsist...

Selenite and selenocystamine [(CyaSe)2] efficiently activate the decomposition of H2O2 by GSH and by other thiols, as demonstrated using a leuco crystal violet POD-based H2O2 assay which is applicable (unlike other assays) also in presence of thiols. The GPx-like activities were estimated to be 3.6 and 2.7 mumol H2O2/min per mumol SeO3(2-) and (CyaSe)2, respectively. Both selenium compounds als...

BACKGROUND Only around 60% of skin lesions excised by GPs are referred to a pathologist. Clinical diagnoses of skin excisions by GPs may not be very accurate. Subcutis excisions are rarely done by GPs, and there is hence little information in the literature on the histopathological yield of subcutis excisions by GPs with regard to malignancies. The aim of this study was to evaluate the yield of...