The objective of this review is to provide an overview of the implication of amino acids (AA) in important physiological functions. This is done in the context of pig production where the competition for AA utilisation is exacerbated by constraints to maximise productive responses and the necessity to reduce dietary protein input for environmental, economic and sanitary issues. Therefore, there...

Accurate timing over the subsecond scale is essential for a range of human perceptual and motor activities, but the mechanisms for encoding this time scale remain poorly understood. Current research is beginning to call into question traditional ideas that events are timed by a centralized supramodal clock, in favor of distributed, modalityspecific mechanisms1. Two recent studies from visual ps...

A mutant malic enzyme gene, mae2-, was cloned from a strain of Schizosaccharomyces pombe that displayed almost no malic enzyme activity. Sequence analysis revealed only one codon-altering mutation, a guanine to adenine at nucleotide 1331, changing the glycine residue at position 444 to an aspartate residue. Gly-444 is located in Region H, previously identified as one of eight highly conserved r...

1Copyright, David M. Mount, 2013, Dept. of Computer Science, University of Maryland, College Park, MD, 20742. These lecture notes were prepared by David Mount for the course CMSC 425, Game Programming, at the University of Maryland. Permission to use, copy, modify, and distribute these notes for educational purposes and without fee is hereby granted, provided that this copyright notice appear i...

Such basic geometric problems are fundamental to computer graphics, and over the next few lectures, our goal will be to present the tools needed to answer these sorts of questions. (By the way, a good source of information on how to solve these problems is the series of books entitled “Graphics Gems”. Each book is a collection of many simple graphics problems and provides algorithms for solving...

Viewing in OpenGL: Today we will discuss how viewing and perspective transformations are handled for 3-dimensional scenes. In OpenGL, and most similar graphics systems, the process involves the following basic steps, of which the perspective transformation is just one component. We assume that all objects are initially represented relative to a standard 3-dimensional coordinate frame, in what a...

1. Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 419 1.1. Liver Disease and Cell-Based Therapies . . . . . . . . . . . . . . . . . . . . . . . . 419 1.2. Cell Sources for Liver Cell-Based Therapies . . . . . . . . . . . . . . . . . . . . 419 1.3. Approaches for the In Vitro Stabilization of Primary Hepatocytes . 420 1.4....

MicroRNAs (miRNAs) play critical roles in hepatocellular carcinoma (HCC) progression and are key determinants of prognosis. In this study, we found that miR-425-5p was elevated in HCC and correlated with poor prognostic clinicopathological features and low post-operative long-term survival. Multivariate survival analysis indicated that miR-425-5p expression was an independent risk factor for ov...