Possible protective effects of the agonist [D-Trp6]LH-RH (analog of luteinizing hormone-releasing hormone in which Gly-6 is replaced by D-tryptophan) and antagonist N-Ac-[D-Phe(pCI)1,2,D-Trp3,D-Arg6,D-Ala10]LH-RH against testicular damage caused by x-radiation were investigated in rats. Three months after being subjected to x-irradiation of the testes with 415 or 622 rads, control rats showed m...

Platelets, protease-activated receptors and fibrinogen in hematogenous metastasis. Short title: Host factors in coagulantdriven bloodborne metastasis Eric Camerer, Aisha A. Qazi, Daniel N. Duong, Ivo Cornelissen, Rommel Advincula, and Shaun R. Coughlin Cardiovascular Research Institute, University of California, San Francisco Supported by NIH HL65590 and HL65185 (S.R.C.). E.C. was supported by ...

Single-mode second-order distributed feedback (DFB) lasers with low threshold, based on polystyrene films doped with 30 wt. % of the hole-transporting organic molecule N,N'-bis (3-methylphenyl)-N,N'-diphenylbenzidine (TPD) are reported. The laser emission wavelength was tuned between 415 and 427 nm by film thickness variation. The effectiveness of the DFB grating in improving the laser performa...

The authors’ goals in this article are to (a) describe a new task for the assessment of shifting attention between different affective stimuli, The Children’s Attentional Shifting Task (CAST); (b) present the theoretical background for the development of the CAST; and (c) report initial information on the developmental appropriateness and validity of the CAST. The task was tested using a sample...

The authors explored whether manipulating the location of distraction in the participants’ visual field influences the degree of competition between visual and other cognitive processes. If a cognitive task is lateralized to a particular hemisphere, visual distraction directed toward that same hemisphere should impair performance on that task more than should visual distraction directed toward ...

We report near-infrared radial velocity measurements of the recently identified donor star in the high mass X-ray binary system OAO 1657–415 obtained in the H band using ISAAC on the VLT. Cross-correlation methods were employed to construct a radial velocity curve with a semi-amplitude of 22.1± 3.5 km s. Combined with other measured parameters of this system this provides a dynamically determin...

Chronic hepatitis C virus (HCV) infection is the most common cause of end-stage liver disease, often leading to liver transplantation, in which case circulating virions typically infect the transplanted liver within hours and viral concentrations can quickly exceed pre-transplant levels. MBL-HCV1 is a fully human monoclonal antibody recognizing a linear epitope of the HCV E2 envelope glycoprote...

The efficacy and safety of incobotulinumtoxinA ≤400 U was demonstrated in subjects with post-stroke upper-limb spasticity a randomized, double-blind Phase 3 study an open-label extension (OLEX; EudraCT number 2005-003951-11, NCT00432666). We report post-hoc analysis the duration treatment effect. Subjects completing placebo-controlled main period (single injection cycle 12-20-week observation) ...

Wednesday, May 28, 2003 9:30 a.m. Meeting with Advisory Committee on the Medical Uses of Isotopes (ACMUI) (Public Meeting) (Contact: Angela Williamson, 301– 415–5030) This meeting will be webcast live at the Web address—http://www.nrc.gov 2:45 p.m. Discussion of Management Issues (Closed—Ex. 2) Thursday, May 29, 2003 9:30 a.m. Briefing on Status of Revisions to the Regulatory Framework for Stea...