1 Medicinal Chemistry, Louvain Drug Research Institute, Université catholique de Louvain. 73, Bte B1.73.10, Av. E. Mounier B-1200 Bruxelles, Belgium. 2 Unité de Formation et de Recherches en Pharmacie, Faculté des Sciences de la Santé, Université d’AbomeyCalavi, BP-188, Cotonou, Bénin. 3 Laboratoire de Pharmacognosie/UAC/CBRST ; Porto-Novo, BP 06 Oganla, Benin. 4 Medicinal Chemistry, School of ...

In this work, we report on a new lead(II) coordination complex [Pb2L2(CH3CN)(ClO4)2]·2H2O (1·2H2O), which was readily synthesized from mixture of Pb(ClO4)2·3H2O and 1-(pyridine-2-yl)benzylidene-4-phenylthiosemicarbazide (HL). The crystal structure analysis 1·2H2O evidenced that the cation is N,N',S-chelated by tridentate pincer type L with formation [PbL]+ species, dimerizes through couple reci...

Thiosemicarbazides are potent intermediates for the synthesis of pharmaceutical and bioactive materials and thus, they are used extensively in the field of medicinal chemistry. The imine bond (-N=CH-) in this compounds are useful in organic synthesis, in particular for the preparation of heterocycles and non-natural β-aminoacids. In this paper the synthesis of some new thiosemicarbazide derivat...

Thiosemicarbazides are potent intermediates for the synthesis of pharmaceutical and bioactive materials and thus, they are used extensively in the field of medicinal chemistry. The imine bond (-N=CH-) in these compounds are useful in organic synthesis, in particular for the preparation of heterocycles and non-natural β-aminoacids.In this paper the synthesis of some new thiosemicarbazide derivat...

Thiosemicarbazides are potent intermediates for the synthesis of pharmaceutical and bioactive materials and thus, they are used extensively in the field of medicinal chemistry. The imine bond (-N=CH-) in these compounds are useful in organic synthesis, in particular for the preparation of heterocycles and non-natural β-aminoacids.In this paper the synthesis of some new thiosemicarbazide derivat...