Background Advanced cell culture models, especially long-term 3D systems, require bioreactors allowing for cultivation under continuous flow conditions. Such culture models are for example tissue engineered implants, 3D cultures for drug testing, in vitro models of cell growth and migration for wound healing studies, cell cultures for biomaterial testing. New challenges in drug testing and biom...

Purpose: The authors report comprehensive commissioning and quality assurance (QA) procedures for Intrabeam, Intra-Operative radiotherapy (IORT) unit. The Intrabeam system miniature X-ray source is a 50 kV and 40 μA unit. Methods: The authors’ tests include measurements of output, beam deflection, isotropy, kVp and mAs measurements, quality index, isodose, reproducibility, linearity, depth dose...

OBJECTIVES The aim of this study was to evaluate feasibility and accuracy of real-time 3-dimensional (3D) echocardiography for quantification of mitral regurgitation (MR), in a head-to-head comparison with velocity-encoded cardiac magnetic resonance (VE-CMR). BACKGROUND Accurate grading of MR severity is crucial for appropriate patient management but remains challenging. VE-CMR with 3D three-...

We report a lab-on-chip device to study liver function enhancement by mimicking a liver tissue with its sinusoid on a 3D biomimetic chip. The device procures a thin polydimethylsiloxane membrane with an array of holes etched in it and sandwiched in the center of the microchannel to form upper and lower microchambers. Hepatocytes and fibroblasts were co-cultured on the upper chamber to mimic liv...

Background: The present work aims to study the out-of-field photon calculation accuracy of a commercial treatment planning system (TPS), Oncentra, for three-dimensional conformal radiotherapy (3D-CRT) and intensity modulated radiation therapy (IMRT) treatment techniques from Elekta Synergy medical linear accelerator. Materials and Methods: Accuracy of individual out-of-field dose components was...

The drying industry has grown considerably due to the tremendous demand for non-perishable food. Convective is one of most popular equipment in (food, chemical, pharmaceutical, etc.). One drawbacks this equipment, when used convective drying, non-uniformity final product quality. This study presents development a numerical model through Computational Fluid Dynamics (CFD). chamber heat pump drye...

This study aimed to describe the commissioning of small field size radiosurgery cones in a 6-MV flattening filter free (FFF) beam and report our measured values. Four radiosurgery cones of diameters 5, 10, 12.5, and 15 mm supplied by Elekta Medical were commissioned in a 6-MV FFF beam from an Elekta Versa linear accelerator. The extraction of a reference signal for measuring small fields in sca...

8 An important component of the Pulsed Electric Field (PEF) technology is the 9 treatment chamber in which the food is exposed to high electric field pulses. A 10 detailed knowledge of the electric field strength and the induced temperature 11 distribution in the chamber is essential to achieve efficient and gentle pasteurisation. 12 Experimental determination of such distributions is extremely...