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Long non-coding RNAs (lncRNAs) regulate oncogenesis by inducing methylation of CpG islands to silence target genes. Here we show that the lncRNA PCAT-14 is overexpressed in patients with hepatocellular carcinoma (HCC), and is associated with a poor prognosis after surgery. Our results demonstrate that PCAT-14 promotes proliferation, invasion, and cell cycle arrest in HCC cells. In addition, PCA...
www.sciencemag.org (this information is current as of July 23, 2007 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/317/5836/372 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/317/5836/372/DC1 can be found a...
Aberrant microRNA (miRNA) expression has been investigated in gastric cancer, which is one of the most common malignancies. However, the roles of miRNAs in gastric cancer remain largely unknown. In the present study, we found that microRNA-372 (miR-372) directly targets tumor necrosis factor, α-induced protein 1 (TNFAIP1), and is involved in the regulation of the NFκB signaling pathway. Further...
INTRODUCTION 363 KI.NETOPLAST MINICIRCLE DNA 365 Is There a Gene Product? 365 Sequence Organization in Different Species 365 Sequence Heterogeneity as a Diagnostic and Epidemiological Tool 368 Analysis of Conformational Bend in Minicircle DNA 370 Replication of Minicircle DNA 371 KINETOPLAST .MAXICIRCLE DNA 372 Mitochondrial Ribosomal R.VA genes 372 Mitochondrial Siruciural Genes and Open Readi...
1Assistant Professor, Susquehanna University, 314 Steele Hall, Selinsgrove, PA 17870 (corresponding author: phone: 570-372-4186; fax: 570-372-2870; e-mail: [email protected]). 2Research Economist, RTI International, Research Triangle Park, NC 27709 (phone: 919-485-5579; fax: 919-541-6683; e-mail: [email protected]). 3Assistant Professor, Kenyon College, Gambier, OH 43022 (phone: 740-427-5281; fax: 7...
Medical History / Volume 48 / Issue 03 / July 2004, pp 367 372 DOI: 10.1017/S0025727300007687, Published online: 26 July 2012 Link to this article: http://journals.cambridge.org/abstract_S0025727300007687 How to cite this article: Christine Nutton and Vivian Nutton (2004). Noël du Fail, Cardano, and the Paris Medical Faculty. Medical History, 48, pp 367-372 doi:10.1017/S0025727300007687 Request...
مقدمه: سرطان معده، از متداول ترین سرطان ها در جهان و دومین عامل مرگ انسان در اثر سرطان است. micrornas گروهی از rnaهای درون زاد کوچک غیر کد کننده با طول 23-21 نوکلئوتید هستند. افزایش بیان 372-mir در برخی سرطان ها، با کاهش بیان هدف آن (2lats) نقش انکومیری دارد. کاهش بیان 2lats منجر به عدم تنظیم چرخه ی سلولی، آپوپتوز و تکثیر سلولی می گردد. روش ها: در این مطالعه، با استفاده از ترانسداکشن لنتی ویروس...
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