Ascorbate (AH, the reduced form of vitamin C) is an important radical scavenger and antioxidant in human plasma; the resulting ascorbyl radical can disproportionate to AH and dehydroascorbic acid (DHA). Here we address potential maintenance mechanism(s) for extracellular AH by examining the ability of cells to convert extracellularly presented DHA to AH. DHA was rapidly transported into human l...

A new antiherpetic agent, AH-758, was isolated from the culture broth of Streptomyces sp. strain No. 758. The structure was determined by NMR special analyses to be a new antibiotic belonging to bafilomycin group containing (5-oxo-2-pyrrolin-2-yl) methyl fumarate in its C-21.

Let φ(x1, . . . , xh, y) = u1x1 + · · · + uhxh + vy be a linear form with nonzero integer coefficients u1, . . . , uh, v. Let A = (A1, . . . , Ah) be an h-tuple of finite sets of integers and let B be an infinite set of integers. Define the representation function associated to the form φ and the sets A and B as follows: R (φ) A,B (n) = card ({(a1, . . . , ah, b) ∈ A1 × · · · × Ah × B : φ(a1, ....

AIM The purpose of this study was to determine whether AH 26 and AH Plus have in vitro oestrogenic effects. METHODOLOGY MCF-7 breast cancer cells were trypsinized and plated in 24-well plates at initial concentrations of 10,000 cells per well in 5% FBS in DME. Cells were allowed to attach for 24 h; then the seeding medium was replaced with 10% CDHuS-supplemented phenol red-free DME. Different...

Memon, Riaz A., John Fuller, Arthur H. Moser, Kenneth R. Feingold, and Carl Grunfeld. In vivo regulation of plasma platelet-activating factor acetylhydrolase during the acute phase response. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R94–R103, 1999.—Plasma plateletactivating factor acetylhydrolase (PAF-AH) hydrolyzes PAF and oxidized phospholipids and is associated with lip...