OBJECTIVE To study the efficacy and safety of monochromatic excimer light (MEL) on 37 vitiligo patients referred to our clinic. METHODS In a pilot study, 37 patients (17 males, 20 females) with acrofacial (n=21), focal (n=11), segmental (n=1), and generalized (n=4) vitiligo were treated twice weekly with MEL for a maximum period of 6 months. RESULTS Thirty-five patients (95%) showed signs o...

OBJECTIVE To determine the response of stubborn psoriatic plaques to the 308-nm excimer laser. DESIGN Controlled study with a before-after design. SETTING A university-based clinical research center. PATIENTS Adult subjects with recalcitrant plaque psoriasis that have not responded to other therapies for at least 2 months. INTERVENTIONS Selected psoriatic plaques were treated with the 3...

Vol. 30, No. 1, 2018 93 Received September 20, 2016, Revised November 28, 2016, Accepted for publication December 22, 2016 Corresponding author: Moon-Bum Kim, Department of Dermatology, Pusan National University Hospital, 179 Gudeok-ro, Seo-gu, Busan 49241, Korea. Tel: 82-51-240-7338, Fax: 82-51-245-9467, E-mail: [email protected] This is an Open Access article distributed under the terms of th...

OBJECTIVE To determine the dose-response relationship of excimer laser-generated 308-nm UV-B radiation for treating psoriasis. DESIGN Pilot study with a before-after design. SETTING A university dermatology service. PATIENTS Thirteen consecutive patients with at least 4 large, stable psoriasis plaques. INTERVENTIONS Excimer laser-generated 308-nm UV-B radiation was given to each of 4 pl...

The relative safety and thrombogenicity of pulsed excimer and thermal laser angioplasty systems were compared in 20 normal coronary artery segments in a total of seven pigs. Using similar over the wire catheter systems and laser delivery periods of 3 to 5 s, thermal laser angioplasty was achieved with a 1.3 mm metal probe heated with 10 W of continuous argon laser energy and excimer laser angio...

Vit i l igo i s an acquired depigmentat ion disorder of the skin in which there is loss of epidermal melanocytes. The prevalence of vitiligo is approximately 0.1-2% worldwide. The precise pathogenesis of vitiligo remains subtle and is probably multifactorial 1. Treatment of vitiligo remains an interesting topic and many centers have been reported as having varying degrees of success. Medical th...

BACKGROUND The excimer laser delivers targeted ultraviolet B 308-nm radiation. OBJECTIVE This investigation evaluated the efficacy of multiple, medium-dose excimer 308-nm laser treatments for psoriasis. METHODS Twenty volunteers with plaque psoriasis were enrolled. Six plaques received treatment 3 times per week for up to 8 weeks; another plaque served as a control. As in standard photother...