BACKGROUND The objective of this study is to evaluate the diagnostic utility of digital rectal examination (DRE), prostate specific antigen (PSA) and transrectal ultrasonography (TRUS) for prostate cancer. METHODS On 266 patients ultrasonography guided transrectal biopsies were performed using the automatic biopsy gun fitted with an 18 gauge biopsy needle. RESULTS There was no major complic...

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OBJECTIVES The aim of this study was to examine the relative frequency of odontogenic tumours at a tertiary hospital in Ibadan, as well as to study the various histologic types based on WHO 2005 classification and to compare results from this study with those of previous studies. STUDY DESIGN The records of the Oral Pathology Department of University College Hospital were reviewed. Lesions di...

........................................................................................................................................................................... 198 Introduction ...................................................................................................................................................................... 199 Material and Methods ...................

Background. S-649266 (’266) is a novel catechol-substituted siderophore cephalosporin for injection discovered by Shionogi and Co., Ltd. In this study, in vitro antibacterial activity of ’266 is evaluated against the clinical isolates of Gram-negative bacteria. Methods. MIC was measured by broth microdilution method according to Clinical and Laboratory Standard Institute except that CAMHB suppl...

It has been reported that the hyperinsulinism-hyperammonemia syndrome is caused by mutations in glutamate dehydrogenase (GDH) gene that affects enzyme sensitivity to GTP-induced inhibition. To identify the GTP binding site(s) within human GDH, mutant GDHs at Tyr-266 or Lys-450 position were constructed by cassette mutagenesis. More than 90% of the initial activities were remained at the concent...