نتایج جستجو برای: 225
تعداد نتایج: 11288 فیلتر نتایج به سال:
For forecasting volatility of futures returns, the paper proposes an indirect method based on the relationship between futures and the underlying asset for the returns and time-varying volatility. For volatility forecasting, the paper considers the stochastic volatility model with asymmetry and long memory, using high frequency data for the underlying asset. Empirical results for Nikkei 225 fut...
We have previously described anti-epidermal growth factor (EGF) receptor monoclonal antibodies (MAbs) which can block binding of transforming growth factor alpha (TGF-alpha) and EGF to receptors and inhibit activation of receptor tyrosine kinase. Studies with these MAbs involving cell cultures and nude mouse xenografts demonstrated their capacity to inhibit the growth of a variety of tumor cell...
Radium needles that were once implanted into tumours as a cancer treatment are now obsolete and constitute a radioactive waste problem, as their half-life is 1600 years. The reduction of radium by photonuclear transmutation by bombarding Ra-226 with high-energy photons from a medical linear accelerator (linac) has been investigated. A linac dose of 2800 Gy produced about 2.4 MBq (64 microCi) of...
BACKGROUND We have previously demonstrated the epidermal growth factor receptor (EGFR)-targeted hybrid plasmonic magnetic nanoparticles (225-NP) produce a therapeutic effect in human lung cancer cell lines in vitro. In the present study, we investigated the molecular mechanism of 225-NP-mediated antitumor activity both in vitro and in vivo using the EGFR-mutant HCC827 cell line. METHODS The g...
*Reza Kiani, MD, MRCPsych Specialist Registrar/Honorary Lecturer in Psychiatry of Learning Disability, and Honorary Specialist Registrar, National Deaf Services. Leicester Frith Hospital, Leicester, UK Tel: 0116 225 5273 Fax: 0116 225 5272 email: [email protected] Satheesh Kumar Gangadharan, MD, MRCPsych Consultant in Psychiatry of Learning Disability, Leicester Frith Hospital, Leicester, UK T...
BACKGROUND Vascular endothelial growth factor A (VEGFA), a critical mediator of tumor angiogenesis, is a well-characterized target of hypoxia-inducible factor 1 (HIF-1). Murine arrest-defective protein 1A (mARD1A(225)) acetylates HIF-1alpha, triggering its degradation, and thus may play a role in decreased expression of VEGFA. METHODS We generated Apc(Min/+)/mARD1A(225) transgenic mice and qu...
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