Combination chemotherapy is often used to treat cancer. Many studies have shown schedule-dependent effects between anticancer drugs. Our previous studies showed that K-562 cells pretreated with non-cytotoxic concentrations of 4-hydroperoxycyclophosphamide (4-HPC), which is a preactivated analog of cyclophosphamide (CY), enhanced the cytotoxicity of etoposide (VP-16). The appearance of cellular ...

BACKGROUND To compare the prognostic value of different anatomical and functional metabolic parameters determined using [(18)F]FDG-PET/CT with other clinical and pathological prognostic parameters in cervical cancer (CC). METHODS Thirty-eight patients treated with standard curative doses of chemo-radiotherapy (CRT) underwent pre- and post-therapy [(18)F]FDG-PET/CT. [(18)F]FDG-PET/CT parameter...

[PDF] [Full Text] [Abstract] , January 1, 2004; 96 (1): 195-202. J Appl Physiol S. K. Hunter, A. Critchlow, I.-S. Shin and R. M. Enoka in men and women matched for strength Fatigability of the elbow flexor muscles for a sustained submaximal contraction is similar [PDF] [Full Text] [Abstract] , June 1, 2004; 96 (6): 2125-2132. J Appl Physiol S. K. Hunter, A. Critchlow, I.-S. Shin and R. M. E...

Objective: To compare the frequency of wound infection with absorbable suture and non-absorbable after cesarean section. Study Design: A randomized controlled trial. Place Duration: Department Obstetrics Gynaecology, Nisthar Hospital, Multan from August 2021 to June 2022. Methodology: total 826 women (413 in each group) undergoing section were included. In Group-A was employed while Group-B, us...

Eosinophil cationic protein (ECP) is a cytotoxic protein produced by and secreted from human eosinophil granulocytes. ECP may be involved in the injury of epithelial cells in allergic diseases such as asthma. The objectives were to determine the prevalence of the ECP gene polymorphism 562(G > C) in apparently healthy subjects and subjects with allergy and relate the prevalence to clinical disea...

agers may organise the collection of resources and their transportation back to the nest. One way is to partition the task into a number of sequential stages in which material is passed from one worker to another in a relay fashion. This relatively new concept is known as task partitioning. In this study, we focus on a particular form of task partitioning, bucket brigades, which we define as a ...

The human liver cell line HepaRG has been recognized as a promising source for in vitro testing of metabolism and toxicity of compounds. However, currently the hepatic differentiation of these cells relies on exposure to dimethylsulfoxide (DMSO), which, as a side effect, has a cytotoxic effect and represses an all-round hepatic functionality. The AMC-bioartificial liver (AMC-BAL) is a three-dim...