conclusions the kin gingival chlorhexidine mouthwash has a greater effect than behsa and boht mouthwashes on oral microorganisms and is recommended to be used for plaque chemical inhibition. results the mics for kin gingival, behsa and boht mouthwashes were 0.14, 0.48 and 1000 micrograms/ml using the tube method for s. mutans, respectively. the mbcs for the mentioned mouthwashes were 0.23, 1.9 ...

A new series of imidazo[2,1-b]thiazole analogs containing a methyl sulfonyl COX-2 pharmacophore was synthesized and evaluated for their COX-2 inhibitory activity. According to in-vitro COX-1/COX-2 inhibition data, all compounds (6a-g) were selective inhibitors of COX-2 isoenzyme with IC50 values in the highly potent 0.08-0.16 mM range. These results indicated that both potency and selectivity o...

A new series of imidazo[2,1-b]thiazole analogs containing a methyl sulfonyl COX-2 pharmacophore was synthesized and evaluated for their COX-2 inhibitory activity. According to in-vitro COX-1/COX-2 inhibition data, all compounds (6a-g) were selective inhibitors of COX-2 isoenzyme with IC50 values in the highly potent 0.08-0.16 mM range. These results indicated that both potency and selectivity o...

Full-length cDNAs encoding macrophage inhibitory factor-2 (MIF-2) were cloned from Teladorsagia circumcincta (TcMIF-2) and Haemonchus contortus (HcMIF-2). TcMIF-2 HcMIF-2 cDNA (342 bp) encoded proteins of 114 amino acids, each which was present as a single band about 16 kDa on SDS-PAGE. Multiple alignments the protein sequences showed homology 84% between HcMIF-2, 54–76% with MIF-2s seven nemat...