The formation of new capillaries (angiogenesis) may be of clinical importance in facilitating reperfusion and regeneration of hibernating cardiac tissue after myocardial infarction and in microvascular ischemia. Evidence is accumulating that as part of the response to hypoxia, bone marrow-derived circulating endothelial progenitor cells (CEPs) are mobilized and subsequently differentiate into p...

Philip M. Chang, MD, FHRS, CEPS, Akash R. Patel, MD, FHRS, CEPS, Peter Aziz, MD, FHRS, CEPS, Maully J. Shah, MBBS, FACC, FHRS From the Keck School of Medicine of University of Southern California (USC), Keck Medical Center of USC, Los Angeles, California, University of California San Francisco (UCSF) School of Medicine, UCSF Benioff Children’s Hospital, San Francisco, California, Cleveland Clin...

physiological processes such as wound healing and tumor growth require endothelial migration, proliferation, and stabilization, a process referred to as angiogenesis. Initial phases of angiogenesis involve the recruitment of endothelial cells to the site of injury or to the tumor vascular bed. Two possible sources of endothelialization are (a) migration and co-option (1, 2) of preexisting vascu...

Chiral exceptional points (CEPs) have been shown to emerge in traveling wave resonators via asymmetric back scattering from two or more nano-scatterers. Here, we provide a new perspective on the formation of CEPs based coupled oscillator model. Our approach provides an intuitive understanding for modal coalescence that signals emergence CEPs, and emphasizes role played by dissipation throughout...

In this research, CaO (calcium oxide) nanoparticles were synthesized by Co-Precipitation method in the absence and presence of Polyvinylpyrrolidone (PVP) via using calcium (II) nitrate. The Polyvinylpyrrolidone (PVP) was used as a capping agent to control the agglomeration of the nanoparticles. The synthesized samples were characterized via SEM, XRD and FTIR techniques. The average sizes of nan...

PURPOSE The aim of this study was to evaluate and compare tooth surface characteristics in extracted human molars after cervical enamel projections (CEPs) were removed with the use of three rotating instruments. METHODS We classified 60 extracted molars due to periodontal lesion with CEPs into grade I, II, or III, according to the Masters and Hoskins' criteria. Each group contained 20 specime...

Jane E. Crosson MD, FACC, David J. Callans MD, FHRS, FACC, FAHA, David J. Bradley MD, FACC, FAAP, Anne Dubin MD, FHRS, FAHA, FACC, Michael. Epstein MD, FACC, CCDC, Susan Etheridge MD, FHRS, FACC, FAAP, CEPS, Andrew. Papez MD, FHRS, CCDS, John Phillips MD, FAAP, FHRS, FACC, Larry Rhodes MD, FAAP, FHRS, FACC, Philip Saul MD, FHRS, FACC, FAHA, Elizabeth Stephenson MD, MSc, FHRS, CCDS, CEPS, Willia...

Generalization, i.e., the ability of solving problem instances that are not available during system design and development phase, is a critical goal for intelligent systems. A typical way to achieve good generalization learn model from vast data. In context heuristic search, such paradigm could be implemented as configuring parameters parallel algorithm portfolio (PAP) based on set “training” i...

Low-dose metronomic chemotherapy is a promising therapeutic cancer treatment strategy thought to have an antiangiogenic basis. However, the advantages of reduced toxicity, increased efficacy in some cases, and ability to combine chemotherapy administered long term in this way with targeted therapies can be compromised by the empiricism associated with determining the optimum biologic dose (OBD)...

The objective of this study was to determine whether cortical evoked potentials (CEPs) can define neurophysiological patterns in irritable bowel syndrome (IBS). In this prospective study of consecutive patients attending secondary and tertiary centers, patients with Rome II-defined IBS underwent rectal sensory and pain threshold (RST and RPT, respectively) testing with electrical stimulation on...