The acetylation modification process of histone has an essential role in the epigenetic regulation gene expression. This is controlled by balance between deacetylases (HDAC) and acetyltransferases (HAT). HDACs are thought to be vital for cell function. Particularly, higher HDAC expression frequent various cancers, resulting dysregulation several target genes involved proliferation, differentiat...

In the title salt, C(5)H(8)N(3) (+)·C(7)H(6)NO(2) (-), the pyridine N atom of the 2,3-diamino-pyridine mol-ecule is protonated. The proton-ated N atom and one of the two N atoms of the 2-amino groups are hydrogen bonded to the 3-amino-benzoate anion through a pair of N-H⋯O hydrogen bonds, forming an R(2) (2)(8) ring motif. The carboxyl-ate mean plane of the 3-amino-benzoate anion is twisted by ...

In the title compound, [Ni(2)(CO(3))(C(5)H(6)N(2))(8)(H(2)O)]Cl(2)·5H(2)O, one of the the Ni(II) ions is six-coordinated in a distorted octa-hedral geometry, with the equatorial plane defined by four pyridine N atoms from four amino-pyridine ligands, the axial positions being occupied by one water O and a carbonate O atom. The other Ni(II) ion is also six-coordinated, by four other pyridine N a...

In the title compound, [Ni(C(8)H(7)O(3))(NO(3))(C(12)H(12)N(2))(2)], the asymmetric unit contains a Ni(II) atom, two mol-ecules of 2-(benzyl-amino)pyridine, a mol-ecule of deprotonated o-vanillin (3-methoxy-salicylaldehydate) and a bidentate nitrate anion. The Ni(II) center is six-coordinated by two pyridine N atoms from 2-(benzyl-amino)pyridine, two O atoms from o-vanillin and two O atoms from...