to find the protective role of exogenous nitric oxide (no) on salinity-stressed rice seedlings, a crd-based factorial experiment with three replications was conducted in agronomy laboratory of the faculty of agricultural sciences, university of guilan, in 2012. the experimental design consisted of healthy and vigorous seedlings of two rice cultivars, khazar and goohar, the last already known as...

drought stress is one of the serious problems that restricted agronomic plant production worldwide. inmolecular level, the harmful effect of drought stress is mostly caused by producing of large amount ofreactive oxygen species (ros). catalase and metallothionein genes have a crucial role to mope the hydrogenperoxide (h2o2) resulting reducing oxidative damage. in this research the gene expressi...

background: lead, an example of heavy metals, has, for decades, being known for its adverse effects on various body organs and systems such that their functions are compromised. objective: in the present study, the ability of lycopersicum esculentum on decrease toxic effects of lead acetate on plasma superoxide dismutase, catalase and malondialdehyde in rat. lead to adversely affect the liver t...

Neutrophils are the first line of defense against bacterial infections, and the generation of reactive oxygen species is a key part of their arsenal. Pathogens use detoxification systems to avoid the bactericidal effects of reactive oxygen species. Here we demonstrate that the Gram-negative pathogen Pseudomonas aeruginosa is susceptible to reactive oxygen species but actively blocks the reactiv...

Background: It is assumed giving oxygen to patients with acute myocardial infraction may increase the oxygenation of the ischemic tissue; however, the usefulness of oxygen in these patients has become a challenging topic. Thus, the present study aimed to determine the effect of oxygen inhalation on cardiac biomarkers in patients with acute myocardial infarction.    Methods: This randomized cli...

6- mercaptopurine (6-mp) is widely used in clinic as an immunosuppressive for treatment of acute lymphocytic leukemia, crohn's disease, and ulcerative colitis with documented unpredictable hepatotoxicity. the potential molecular cytotoxic mechanisms of 6-mp against isolated rat hepatocytes were searched in this study using “accelerated cytotoxicity mechanism screening (acms)” techniques. t...

background: the progressive accumulation of misfolded and aggregated proteins in neurons is an accepted mechanism in aging. overproduction of reactive oxygen species (ros), referred to as oxidative stress, is currently believed to play a pivotal role in this process. lipofuscin as a histological index of aging results from cross-links between oxidized proteins and lipids. therefore, to attenuat...

background: reactive oxygen species (ros) are a group of free radicals that in excessive amounts have negative influence on sperm quality and function. objective: to study the effect of varicocele and its severity on the level of ros in infertile men with clinical varicocele. materials and methods: in this controlled prospective study, 42 men with clinically diagnosed left varicocele and 30 fer...

background: reactive oxygen species (ros) are a group of free radicals that in excessive amounts have negative influence on sperm quality and function. objective: we compared ros levels in seminal plasma of infertile men with this level in healthy donors. we also determined the ros level in semen of infertile men according to the etiology of infertility, and also the effect of smoking on its le...

objective: oxidative stress plays a key role in the pathophysiology of brain ischemia and neurodegenerative disorders.previous studies indicated that viola tricolor and viola odorataare rich sources of antioxidants. this study aimed to determine whether these plants protect neurons against serum/glucose deprivation (sgd)-induced cell death in an in vitro model of ischemia and neurodegeneration....