A series of 2-mercaptobenzimidazole derivatives (MB1–MB5) were synthesized by mannich reaction. The purity of synthesized compounds were determined by melting point and TLC and their structure was established by various analytical techniques such as IR and 1HNMR spectral studies. The newly synthesized compounds were screened for anti-inflammatory activities on carrageenan induced paw oedema in ...

Dyes present in the effluent of textile industries are recalcitrant molecules difficult to be degraded biologically. In this study we used Pseudomonas fluorescens to degrade Direct Orange 102 dye. Pseudomonas fluorescens NCIM 2100 was obtained from National Chemical Laboratory, Pune, India, that was adapted to grow on Direct Orange 102. The dye was subjected to degradation by the bacterium and ...

CuO nanoparticle was found to be an efficient catalyst for the synthesis of flavanones derivatives from the reactions between 2-hydroxyacetophenones and aromatic aldehydes at room temperature. The protocol offers advantages in terms of higher yields, short reaction times, and mild reaction conditions, with reusability of the catalyst. The structures of the synthesized substituted flavanones wer...

Cis-polybutadiene was functionalized using in–situ generated DMD as oxidant and tetra-n-butyl ammonium bromide as phase transfer catalyst (PTC). The epoxidation process was investigated by 1HNMR spectroscopy. 1HNMR spectrum analysis of products confirms the absence of ring opening side products in epoxidation reaction. Various factors such as reaction temperature, reaction time and the concentr...

Several substituted-benzimidazole 3-(4-{5-Amino-6-fluoro-1-[2'-(1H-tetrazole-5-yl)-biphenyl-4ylmethyl]-1H-benzoimidazol-2-yl}-phenyl) -2-(substituted)thiazolidin-4-one were synthesized by condensation of various steps with various substituted aryl aldehydes reaction. Elemental analysis, IR, 1HNMR and mass spectral data confirmed the structure of the newly synthesized compounds. Synthesized and ...

A series of novel 3, 4-methylenedioxybenzene scaffold incorporated 1,3,5-trisubstituted-2-pyrazoline derivatives was synthesised as potent antitubercular agents via chalcone intermediates by reaction with hydrazines. The structures of the compounds were confirmed by IR, 1HNMR, 13CNMR and mass spectral data. The novel pyrazolines were screened for in vitro antitubercular activity by almar blue d...