Dynamic remodeling of the actinomyosin cytoskeleton is integral to many biological processes. It is regulated, in part, by myosin phosphorylation. Nonmuscle myosin H chain IIA is phosphorylated by protein kinase C (PKC) on Ser(1917). Our aim was to determine the PKC isoform specificity of this phosphorylation event and to evaluate its potential role in regulated secretion. Using an Ab against t...

Bill Paton's principal career was in experimental pharmacology, and from his student days he was marked for distinction. He took first class honours at Oxford University and won gold medals during his clinical training at University College Hospital. He was a Reader at the age of 35, a Professor two years later, and a Fellow of the Royal Society before he was 40. He returned to Oxford as Profes...

there is a statistically-based portrait, but the author's findings are largely negative. The group was older (a natural consequence of their training and careers before politics) and initially they were more likely to identify with political parties of the left, until the whole character of the legislature itself shifted in that direction by the end of the century. But for the most part, the ph...

Sir Andrew Huxley (1917-2012) pioneered the physiology and biophysics of nerve conduction, skeletal muscle activation and tension generation. His ground-breaking work on nerve excitability of nerve in collaboration with Alan Hodgkin in the Cambridge Physiological Laboratory and the Plymouth Marine Biological Laboratory provided the basis for our understanding of how voltage-gated ion channels g...

Harold Frederick Schuknecht, MD, Professor Emeritus of the Department of Otology and Laryngology at Harvard Medical School and Chief Emeritus of the Department of Otolaryngology at the Massachusetts Eye and Ear Infirmary, who has died, at the age of 79, on October 19, 1996, was a world renowned clinical otologist, otopathologist, teacher and scholar. Harold Schuknecht was born in South Dakota i...

In this study, the authors collected 63 species, of which 15 species are only recorded in Vietnam, 2 described new to science, 8 distributed western north that is not found other regions, including: Eopycna indochinensis (Distant, 1913), Gaeana vitalisi Terpnosia rustica 1917), mesonotalis Semia majuscula Karenia hoanglienensis (Pham & Yang, 2012), Huechys tonkinensis 1917); and Scieroptera...

The New World species of the genus Cremnops are revised. Thirty-three species of Cremnops are treated; five are described as new, i.e., C. bertae sp. nov., C. cluttsis sp. nov., C. nymphius sp. nov., C. wileycoyotius sp. nov. and C. witkopegasus sp. nov. Six species are synonymized, i.e., Cremnops caribensis Berta, 1998, is synonymized under C. guanicanus Wolcott, 1924; C. nigrosternum (Morriso...

We put aside our sadness at the death of Erika Sutter, at the impressive age of 98, to celebrate the life of a truly remarkable pioneering ophthalmologist and inspirational human being. Some of the Community Eye Health Journal’s readers will have been touched by Erika’s powerful promotion of community development in her capacity as an ophthalmologist, a teacher at the International Centre for E...