introduction:myocardial 18f-fdg uptake is highly variable in oncologic whole body 18f-fdg pet/ct studies, ranging from quite intense to minimal distribution. intense or heterogeneous myocardial 18f-fdg uptake is undesirable as it may interfere with the visual or quantitative evaluation of tumoral invasion and metastases in pericardium, myocardium or adjacent mediastinal structures. the diet, as...

introduction:brain imaging with f-18 fluorodeoxyglucose (18f-fdg) positron ‎emission tomography or tc-99m hexamethylpropyleneamine oxime (‎99mtc-hmpao) spect is widely used for the evaluation of alzheimer's ‎dementia (ad); we aim to assess superiority of one method over the ‎other. methods: twenty four patients with clinical diagnosis of alzheimer disease ‎underwent 18f-fdg pet and ‎99mtc-...

objective(s): the study objective was to assess the diagnostic performance of positron emission tomography (pet) for gliomas using the novel tracer 18f-fluciclovine (anti-[18f]facbc) and to evaluate the safety of this tracer in patients with clinically suspected gliomas.methods: anti-[18f]facbc was administered to 40 patients with clinically suspected high- or low-grade gliomas, followed by pet...

An inflammatory pseudotumor (IPT) is a rare benign lesion, characterized by nonneoplastic proliferation of inflammatory cells and presence of intermingling collagen fibers. IPT commonly occurs in the lungs and orbita, while an intraspinal IPT is extremely rare. IPT can mimic both clinically and radiologically malignant processes, and making a definitive preoperative diagnosis is often difficult...

objective(s): in clinical practice, approximately 10-25% of post-surgical differentiated thyroid carcinoma (dtc) patients with high serum thyroglobulin (tg) and negative 131i whole-body scan (wbs) have poor prognosis due to recurrent or metastatic lesions after radioactive iodine treatment. the purpose of this study was to evaluate the value of 18f-fdg pet/ct scan in dtc patients with high seru...

BACKGROUND 18F-FDG PET has been used in sarcoidosis for diagnosis and determination of the extent of the disease. However, assessing inflammatory lesions in cardiac sarcoidosis using 18F-FDG can be challenging because it accumulates physiologically in normal myocardium. Another radiotracer, 3'-deoxy-3'-18F-fluorothymidine (18F-FLT), has been investigated as a promising PET tracer for evaluating...

PURPOSE This is a clinical study to compare noninvasive hypoxia imaging using 18F-fluoroerythronitroimidazole (18F-FETNIM) and 18F-fluoromisonidazole (18F-FMISO) positron emission tomography/computed tomography (PET/CT) in patients with inoperable stages III-IV lung cancer. METHODS A total of forty-two patients with inoperable stages III-IV lung cancer underwent 18F-FETNIM PET/CT (n = 18) and...

In a mouse model of human lung cancer, intratumoral distribution between 3'-deoxy-3'-[18F] fluorothymidine (18F-FLT) and [18F] fluorodeoxyglucose (18F-FDG) was mutually exclusive. 18F-FLT primarily accumulated in proliferating cancer cells, whereas 18F-FDG accumulated in hypoxic cancer cells. The aim of the present study was to evaluate these preclinical findings in patients with lung cancer. A...

Objective(s): We aim to investigate the clinical impact of 18F-FDG PET/CT in managing patients with gynecological malignancies and pelvic or extrapelvic lymph nodes that are of equivocal significance on conventional imaging.Methods: We retrospectively evaluated 18F-FDG PET/CT scans of patients with gynecologic tumors who were referred to King Hussein Cancer Center from January 2010 to August 20...

objective(s): this study aimed to compare the diagnostic values of 11c-choline and 18f-fluorodeoxyglucose (18f-fdg) positron emission tomography/computed tomography (pet/ct) in patients with cholangiocarcinoma (cca). methods: this prospective study was conducted on 10 patients (6 males and 4 females), aged 42-69 years, suspected of having cca based on ct or magnetic resonance imaging (mri) resu...