Mononuclear leukocytes are able to destroy tumor cells under a variety of circumstances. In few such instances is the biochemical basis of cytotoxicity understood. Recently, we demonstra ted that activated macrophages, s t imulated by phorbol myristate acetate (PMA), 1 secreted substantial amounts o f hydrogen peroxide (1). The release o f this oxidant from macrophages correlated with the extra...

In the continued search for inhibitors of enoyl-acyl carrier protein (ACP) reductase, we found that four acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761 potently inhibited bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis. Their structures were identified as panosialins A, B, wA, and wB by MS and NMR data. They sho...

Osteosarcoma is a highly malignant cancer that often appears in teenagers. It is the most frequently occurring primary bone tumor, and can easily metastasize, resulting in high mortality. MicroRNAs express abnormally in osteosarcoma, and may function as oncogenes or tumor suppressors. Recent studies showed that microRNA184 (miR-184) is abnormally expressed in multiple tumors, and is involved in...

In this paper we provide a new insight of the previous work of Grosen and Jørgensen [2002]. More precisely, firstly, we investigate the impact of regulatory authorities’ rules on the fair value of company’s liabilities and assets. We study how to choose regulation intervention levels in order to control the shortfall probability of the issuing company. The fact that the regulation rule depends ...

Ni, Cu, Zn, and Pb were measured by atomic absorption spectrometry in sweat samples obtained by the arm-bag technique from 48 healthy adult subjects (33 a” , 15 ) during sauna bathing (15 mm at 93 #{176}C, dry heat). The men sweated more profusely than the women (volume, in milliliters, of sweat collected: mean, SD, and range: 23 ± 12 (355) and 7 ± 3 (2-13), respectively. The concentrations, in...

Differences in haemostatic parameters have been reported among smokers and non-smokers. However the relationships of these parameters with other risk factors of cardiovascular diseases have not been fully determined in Nigerians. We therefore aimed at assessing the relationship between fibrinogen, factor VII (FVII), age, body mass indeks (BMI), systolic blood pressure (SBP) and diastolic blood ...

The contents of FC, somatic coliphages and F-specific bacteriophages were measured in the stabilization pond and stabilization reservoir system of the City of Arad (Israel) in order to determine the efficiency of the treatment process regarding the microorganisms removal. Monitoring was conducted close to one year. Physical and chemical parameters (temperature, pH, BOD5, COD, SS) were also anal...

The present study investigated the functional characteristics of task-sets that were never applied before and were formed only on the basis of instructions. We tested if such task-sets could elicit a task-rule congruency effect, which implies the automatic activation of responses in the context of another task. To this end, a novel procedure was developed that revealed instruction-based task-ru...

The classic Gibbard-Satterthwaite Theorem establishes that only dictatorial voting rules are strategy-proof; under any other voting rule, players have an incentive to lie about their true preferences. We consider a new approach for circumventing this result: we consider randomized voting rules that only approximate a deterministic voting rule and only are approximately strategy-proof. We show t...

Changes in the concentrations of B, Ca, Fe, K, Mg, Mn, Na, P, S, Sr and Zn in the liquid phase in sheep rumen were determined to obtain information on their rate of disappearance from the soluble pool after feeding. Sheep were fed alfalfa (Medicago sativa) hay hourly. The concentration of infused Cr(III)-EDTA into the rumen (over a period of 4 d) was used to establish steady-state conditions, a...