High-speed counter-current chromatography (HSCCC) with a two-phase solvent system composed of n-hexane-ethyl acetate-methanol-water system (5:5:7:5, v/v) was applied to the isolation and purification of alkaloids from the Chinese medicinal plant Evodia rutaecarpa (Juss.) Benth. Five kinds of alkaloids were obtained and yielded 28 mg of evodiamine (I), 19 mg of rutaecarpine (II), 21 mg of evocar...

Selenium containing nucleosides derived from some heterocyclic moieties such as Pyridineselenol, and pyridazineselenol is described herein. Ribosylation of selenol compounds were prepared in good yield by silyation of selenol derivatives with 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose followed by debenzoylation to afford the corresponding free N-nucleosides  and -1-(2,3,5-trihydroxy--D-r...

Six derivatives of novel triazoles were produced from some substituted benzoic acid with thiocarbazide via method grinding. The Chemicals described 1HNMR, IR, and 13CNMR spectra examinations. Produced C2H3N3 examined assessed as reducing corrosion in 0.5 M HCl for low-C steel utilizing procedure losing weight. It was noticed that such chemicals had an encouraging act reducer counter to mild sol...

A greener approach one-pot reaction of (2-oxo-2-phenyl-ethyl sulfanyl)-acetic acid with chalcones in presence a base to afford an unexpected (5-Benzoyl-2-hydroxy-2,4-6-triphenyl-cyclohexyl) – phenyl-methanone product. The proceeds via sequential double Michael addition-aldol mediated three consecutive C-C bonds are formed one pot. procedure has short time, easy workup, and moderate yield produc...

The research included the preparation of two Schiff bases MA1,2 starting from1-methyl-pyrazole-4-carbaldehyde with 4-chloroaniline or 4-amino antipyrine in equal moles presence glacial acetic acid. Then xazepane rings MA (3-6) were prepared from phthalic anhydride maleic anhydride. chemical formulas confirmed using FTIR, 1HNMR, and 13CNMR spectroscopy. toxicity activity compound MA2 against bre...

A new ligand [4-chloro-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylcarb amothioyl) benzamide] (CAP) was synthesized by reaction of P-ChloroBenzoyl isothio cyanate with 4-aminoantipyrine,The characterized micro elemental analysis C.H.N.S.,FT-IR,UV-Vis and1H-13CNMR spectra, some transition metals complex this were prepared and FT-IR, UV-Vis conductivity measurements, magnetic suscep...

The new anti-cancer and water-soluble curcumin derivatives have been synthesized solvent-freely by functionalizing the phenolic group of with various NH compounds to increase water solubility cancerous properties. biological applications drugs investigated against highly potent HepG2 carcinoma cell line. studies showed that could be used in low concentrations (µM/l<1) avoid anti-apoptoti...