sis, protein folding, protein trafficking and intracellular Ca . The exposure of stress which interferes with the functions of the endoplasmic reticulum (ER) causes the accumulation of unfolded protein in the ER lumen. Under the these conditions, termed ER stress, a signal transduction pathway, which is called the unfolded protein response (UPR), is activated to increase the expression of ER st...

The matched asymptotic (singular perturbation) treatment of the nucleation equation [V. A. Shneidman, Sov. Phys. Tech. Phys. 32, 76 (1987); 33, 1338 (1988)] is modified to include finite heating rate effects, which follow the isothermal transient stage. Despite the complicated mathematical structure of the discrete Becker-Doring equation, the obtained analytical solution is shown to be accurate...

The prolonged bleeding times (1) and protection against thrombosis found in Eskimos (2) is thought to be related to a marine diet rich in c0-3-fatty acids (3). Recently, fish oil diets have been shown to modify the course of rheumatoid arthritis (4). In animal models of disease, diet enrichment with eicosapentaenoic acid (EPA), ~ an c0-3-fatty acid present in fish oil, protected the NZB/NZW mou...

from the genus Ligularia (Compositae) plants we have studied the roots of Ligularia tongolensis (FRANCH) HANDMAZZ collected in mountainous areas (altitude: 3600 m) in southwestern China. Ligularia tongolensis is used as a traditional folk medicine in China and its roots can reduce phlegm, relieve coughing and cure pulmonary tuberculosis, urinary track blockages, common cold, and pharyngitis. Ho...

Members Ahti Anttila, Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Liisankatu 21 B, 00170 Helsinki, Finland Ramesh V. Bhat, National Institute of Nutrition, Indian Council of Medical Research, Jamai-Osmania PO, Hyderabad-500 007 AP, India James A. Bond, Chemico-Biological Interactions, Toxcon, 5505 Frenchmans Creek, Durham, NC 27713, USA Susan J. Borgh...