Neutral endopeptidase (NEP, E.C. 3.4.24.11), a widely distributed ectoenzyme, cleaves and inactivates a variety of biologically active peptides, including the tachykinin, substance P (SP). This study was undertaken to determine whether the modulation of SP airway smooth muscle contraction by NEP is age-dependent. We studied the contractile response of isolated tracheal rings from newborn and 12...

The purpose of the present study was to investigate the morphological characteristics of the developing vallate papillae (VP) of Korean native goats using scanning electron microscopy. In prenatal development of the VP, primordia of the VP were observed and the moat was shallowly spread in 60-day-old fetuses. The moat of the vallate papillae was shallowly spread and still undifferentiated in 90...

This set of notes explains the process that Prof. Jones used to develop the FSM for the lab. The lab simulates a vending machine mechanism for automatically identifying coins (dimes and quarters only), tracking the amount of money entered by the user, accepting or rejecting coins, and emitting a signal when a total of 35 cents has been accepted. In the lab, we will only drive a light with the “...

Héctor Pavés. Marine Biologist and Doctoral Student, Universidad Austral de Chile (UACh). Germán Pequeño. Ph.D., Oregon State University, USA. Professor, Instituto de Zoología “Ernst F. Kilian”, Universidad Austral de Chile. Address: Casilla 567, Valdivia, Chile. e-mail: [email protected] Carlos Bertrán. M.Sc., UACh. Doctor, Universidad de Concepción, Chile. Professor, UACh. Luis Vargas. Marine ...

The possible maternal hepatic and reproductive effects of 1,2,4-trichlorobenzene (TCB) were assessed in rats given 0, 36, 120, 360, and 1200 mg/kg/day of TCB on Days 9-13 of gestation. The animals were sacrificed on Day 14 of pregnancy. Maternal deaths (2/9 rats, 6/6 rats) were recorded in the 360 and 1200 mg/kg/day treatment groups and body weight gain was significantly decreased in the 360 mg...

We report gender differences in the epidemiology and outcome after hip fracture from the Scottish Hip Fracture Audit, with data on admission and at 120 days follow-up from 22 orthopaedic units across the country between 1998 and 2005. Outcome measures included early mortality, length of hospital stay, 120-day residence and mobility. A multivariate logistic regression model compared outcomes bet...

OBJECTIVE GH secretagogues and GH-releasing hormone (GHRH) exert a complex cross-talk at the somatotrope cell, and undertake homologous and heterologous desensitization. On the other hand, the discovery of ghrelin as a new factor implicated in the regulation of GH secretion makes a thorough assessment of its properties and cell biology processes mandatory. In order to implement this, three diff...