نتایج جستجو برای: 11 were resistant homozygous
تعداد نتایج: 3789821 فیلتر نتایج به سال:
OBJECTIVES To determine the mechanism of intermediate- and high-level echinocandin resistance, resulting from heterozygous and homozygous mutations in GSC1 (FKS1), in both laboratory-generated and clinical isolates of Candida albicans. METHODS The DNA sequences of the entire open reading frames of GSC1, GSL1 (FKS3) and RHO1, which may contribute to the beta-1,3-glucan synthase of a micafungin...
abstract introduction & objective: enuresis is defined as involuntary voiding. it is a socially disruptive and stressful condition which affects around 15% of five years old children and up to 1% of adults. aim the aim of this study was to assess the efficacy of desmopressin (nasal spray) and oxybutinin combination therapy in treatment of patients with primary nocturnal enuresis that were resis...
Southern cattle ticks, Boophilus microplus (Canestrini) (Acari: Ixodidae), collected in Coahuila, Mexico, were determined to be resistant to permethrin. Discriminating concentration (DC) tests at the LC99 and 2X the LC99 of susceptible ticks produced 0 and 0.5% mortality, respectively, for permethrin. However, measured mortalities for coumaphos and amitraz acaricides were within the expected ra...
Homozygous mutations in cytochrome b-245 chaperone 1 (CYBC1) have been recently described as causing recurrent infections and inflammatory disease an Icelandic cohort a patient from Saudi Arabia, by destabilising the dimerisation of gp91phox with p22phox, manifesting phenotypic chronic granulomatous (CGD). Haematopoietic stem cell transplantation is treatment choice CGD, though experience this ...
The association between TP53 gene polymorphisms and breast cancer (BC) in Brazilian women is a controversial topic. In this cross-sectional study, we evaluated the association between clinical pathological variables and three polymorphisms (TP53*11, TP53*72, and TP53*248) in BC patients and controls. Genomic DNA was extracted from the blood cells of 393 participants; the cancer-free control sub...
PURPOSE Irinotecan (CPT-11) is approved in metastatic colorectal cancer treatment and can cause severe toxicity. The main purpose of our study was to assess the role of different polymorphisms on the occurrence of hematologic toxicities and disease-free survival in high-risk stage III colon cancer patients receiving 5-fluorouracil (5FU) and CPT-11 adjuvant chemotherapy regimen in a prospective ...
Abstract Potato virus Y (PVY) is one of the main diseases tobacco (Nicotiana tabacum). Recent studies indicated that Va gene (Ntab0942120) determines susceptibility crop to PVY, and product interacts with PVY genome-linked protein (VPg) initiate genome translation process, which ultimately leads systemic infection by virus. In this research, cultivar LJ911 was used as receptor material for edit...
Blast is the most common biotic stress leading to the reduction of rice yield in many rice-growing areas of the world, including Malaysia. Improvement of blast resistance of rice varieties cultivated in blast endemic areas is one of the most important objectives of rice breeding programs. In this study, the marker-assisted backcrossing strategy was applied to improve the blast resistance of the...
BACKGROUND Recessive mutations in the NPHS1 gene encoding nephrin account for approximately 40% of infants with congenital nephrotic syndrome (CNS). CNS is defined as steroid-resistant nephrotic syndrome (SRNS) within the first 90 days of life. Currently, more than 119 different mutations of NPHS1 have been published affecting most exons. METHODS We here performed mutational analysis of NPHS1...
چکیده کنه تارتن دو لکه ای tetranychus urticae koch یکی از چندخوارترین آفات شناخته شده محصولات کشاورزی دنیا به حساب می آید. در این بررسی جمعیت تخم و مراحل فعال این کنه در شرایط آلودگی طبیعی و مصنوعی در برگ های 8 رقم لوبیا در سال 1392 در گلخانه و مزرعه تحقیقاتی دانشکده کشاورزی دانشگاه ارومیه موردمطالعه قرار گرفت. آزمایش به صورت طرح کاملاً تصادفی برای شرایط مزرعه در10 تکرار و برای شرایط گلخانه ای...
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