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We aimed at establishing the epidemiologic profile of first epileptic seizures (FES) in the Greek island of Lesvos. During a 1-year period (01/06/2010 to 31/05/2011), cases of FES admitted to the Lesvos General Hospital/addressed by general practitioners/private neurologists were prospectively identified. A total of 45 cases (30 males and 15 females; mean age ± SD of 59.4 ± 28.4 and 58.9 ± 26.8...
BACKGROUND Community-acquired pneumonia (CAP) remains an important cause of morbidity and mortality. Polymerase chain reaction (PCR) has been shown to be more sensitive than current standard microbiological methods and, therefore, may improve the accuracy of microbiological diagnosis for patients with CAP. METHODS Conventional detection techniques and multiplex real-time PCR for atypical bact...
The efficacy of green tea extract with different strengths on selective microorganisms raw chevon was investigated in this study. experiment conducted using completely randomized design (CRD) six treatments (T0 =0 ml tea; T1 =1 T2 =2 T3 =3 T4 =4 and T5=5 tea) having three replications. Drop plate method used for analyzing antimicrobial activity experiment. outcome illustrated a declining microb...
A conjugated-bisimidazolylporphyrin bridged by bis(ethynylfluorene) was synthesized and organized into linear polymer through self-coordination having mean molecular weights, M(w) and M(n), of ~2.1 × 105 Da and ~1.6 × 105 Da, respectively. A large two-photon absorption cross section value of 3.4 × 105 GM (per dimer unit) was observed. This value was comparable to that of the previously reported...
The rate of gain, carcass measurements and three muscles were evaluated in 65 crossbred boars representing 13 litters that were allotted at 4 wk of age to slaughter weight and treatment groups as follows: 1) 105 kg, castrated; 2) 105 kg, intact; 3) 118 kg, intact; 4) 132 kg, intact and 5) 145 kg, intact. One barrow and four boars within a litter constituted a replicate and each replicate was pe...
The endocannabinoid system consists of cannabinoid CB1 and CB2 receptors, of endogenous agonists for these receptors known as ‘endocannabinoids’, and of processes responsible for endocannabinoid biosynthesis, cellular uptake and metabolism. There is strong evidence first, that this system up-regulates in certain disorders as indicated by an increased release of endocannabinoids onto their recep...
Specimens of the euryhaline cyprinodontid fish, Aphanius dispar, collected in salt ponds, were acclimated to salinities of <1 (freshwater), 35 (seawater), 70, 105, and 140 ppt for 4 wk before measurement of oxygen consumption, critical swimming speed, and routine activity level. Oxygen consumption was similar in <1, 35, and 70 ppt (0.18+/-0.07, 0.17+/-0.06, and 0.16+/-0.04 mL h(-1) g(-1), respe...
there has been a highly significant increase in the number of patients with malignant mediastinal tumors in the last four decades. since these lesions are infrequently encountered and there are very few reports in iran concerning this issue, we performed this study to review our institutional experience of medias-tinal masses and to compare differences in the clinical spectrum between our study...
A high-throughput screening campaign was conducted to interrogate a 380,0001 small-molecule library for novel D2 dopamine receptor modulators using a calcium mobilization assay. Active agonist compounds from the primary screen were examined for orthogonal D2 dopamine receptor signaling activities including cAMPmodulation and b-arrestin recruitment. Although themajority of the subsequently confi...
Several studies have shown that renal failure decreases CYP3A activity and that uremic toxins may play a role via transcriptional or translational modifications of cytochrome P450 (P450) enzymes and direct inhibition of P450-mediated metabolism. In this study, we evaluated the relationship between CYP3A activity (using plasma concentration of 4b-hydroxycholesterol as a biomarker) and clinical c...
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