نتایج جستجو برای: 071 and 092
تعداد نتایج: 16827610 فیلتر نتایج به سال:
A somatic activating mutation in AKT1, c.49G>A, pGlu17Lys, that results in elevated AKT signaling in mutation-positive cells, is responsible for the mosaic overgrowth condition, Proteus syndrome. ARQ 092 is an allosteric pan-AKT inhibitor under development for treatment in cancer. We tested the efficacy of this drug for suppressing AKT signaling in cells and tissues from patients with Proteus s...
The prognosis of patients with advanced hepatocellular carcinoma (HCC) is very poor. The AKT pathway is activated in almost half of HCC cases and in addition, long term exposure to conventional drug treatment of HCC, sorafenib, often results in over-activation of AKT, leading to HCC resistance. Therefore, it is important to assess the safety and the efficacy of selective allosteric AKT inhibito...
Session 1 was classified, and began with a presentation by Weatherington on various platforms in use by the US DoD, their signal collection types (described as EO & IR, although IR in general is considered an EO technology, so EO may refer to visible in this case), and growth plans for future capabilities. Fenner Milton then presented on tests by the US Army Night Vision and Electronic Sensors ...
Noonan Syndrome with Multiple Lentigines (NSML, formerly LEOPARD syndrome) is an autosomal dominant "RASopathy" disorder manifesting in congenital heart disease. Most cases of NSML are caused by catalytically inactivating mutations in the protein tyrosine phosphatase (PTP), non-receptor type 11 (PTPN11), encoding the SH2 domain-containing PTP-2 (SHP2) protein. We previously generated knock-in m...
W9 2HU (081 289 611) Disablement Information and Advice Lines (DIAL) UK, DIAL House, 117 High Street, Clay Cross, Derbyshire S45 9D2 (local addresses supplied) English Heritage, Fortress House, 23 Savile Row, London W1Y IAB. Handicapped Piscatorial Association, 29 Ironlatch Avenue, St Leonards on Sea, East Sussex TN38 9JE (0424 427931) Joseph Rowntree Memorial Trust, PO Box 50, York YO1 IUY Nat...
در این بررسی 18 رقم نخود سفید ایرانی از نظر صفات کمی و کیفی مورد مقایسه قرار گرفت و رابطه بین صفات مورد مطالعه مشخص گردید. اختلاف میزان عملکرد‘ مدت پخت و خوش خوراکی درارقام مورد آزمایش از نظر آماری معنی دار بود ولی از لحاظ درصد پروتئین ‘ پروتئین در هکتار ‘ رنگ ‘ یکنواختی اندازه ‘ یکنواختی پختگی ومزه تفا وت معنی داری بین ارقام مشاهده نشد. ضریب همبستگی معنی دار ولی منفی بین مزه با پروتئین ومدت پخ...
"Volume 2022 (2022): Issue 071 (Mar 2022): Bangladesh: 2021 Article IV Consultation-Press Release; Staff Report; and Statement by the Executive Director for Bangladesh" published on 07 Mar International Monetary Fund.
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