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تعداد نتایج: 16839129 فیلتر نتایج به سال:
BACKGROUND The TLR7/8 agonist 3M-052 and the TLR9 agonist CpG ODN both trigger innate immune responses that support the induction of tumor-specific immunity. Previous studies showed that these agonists used individually could improve the survival of mice challenged with small tumors but were of limited therapeutic benefit against large/advanced tumors. METHODS Normal mice were challenged with...
SBS0335-052 is a blue compact dwarf galaxy (BCD) with one of the lowest known metallicities, Z∼Z⊙/41, making it a local example of how primordial starburst galaxies and their precursors might appear. A spectrum obtained with the Infrared Spectrograph (IRS) on the Spitzer Space Telescope clearly shows silicate absorption features, emission lines of [SIV] and [NeIII], and puts strong upper limits...
SBS0335-052 is a blue compact dwarf galaxy (BCD) with one of the lowest known metallicities, Z∼Z⊙/41, making it a local example of how primordial starburst galaxies and their precursors might appear. A spectrum obtained with the Infrared Spectrograph (IRS) on the Spitzer Space Telescope clearly shows silicate absorption features, emission lines of [SIV] and [NeIII], and puts strong upper limits...
Since 1997, highly pathogenic avian influenza viruses of the H5N1 subtype have been transmitted from avian hosts to humans. The severity of H5N1 infection in humans, as well as the sporadic nature of H5N1 outbreaks, both geographically and temporally, make generation of an effective vaccine a global public health priority. An effective H5N1 vaccine must ultimately provide protection against vir...
1The authors thank Trine Poulsen, Annette K. Nielsen, and Kasper B. Poulsen for their skilled technical assistance. The project was fi nancially supported by the Danish Council for Strategic Research (FØSU 2101-07-0111). 2Corresponding author: [email protected] ABSTRACT: Free fatty acids (FFA) are produced in the intestine by microbial fermentation. Recently, a family of G protein-coupled re...
For nearly a century, aluminum salts have been the most widely used vaccine adjuvant formulation, and have thus established a history of safety and efficacy. Nevertheless, for extremely challenging disease targets such as tuberculosis or HIV, the adjuvant activity of aluminum salts may not be potent enough to achieve protective efficacy. Adsorption of TLR ligands to aluminum salts facilitates e...
this study was carried out to investigate the effects of integrative vs. instrumental motivation, learning strategy use and gender on iranian efl learners. to this end, 120 efl learners both male and female majoring in english language and literature at shiraz university participated in the study. in order to conduct this study three instruments were used: oxford quick placement test, motivatio...
abstract the aim of the present study is to explore the impact of the cognitive reading strategy instruction on learners reading self-efficacy and their reading achievement. in order to fulfill this purpose, from 120 participants, 90 intermediate efl learners as an experimental group were chosen from three different educational settings namely, yazd university, yazd science and art un...
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