Background: Indisetron is a serotonin (5-hydroxytryptamine type 3) receptor antagonist that also antagonizes 5-hydroxytryptamine type 4 receptors. We designed a pilot study in order to explore the optimal dosing period for indisetron during modified FOLFOX6 (mFOLFOX6). Patients and Methods: Forty-two chemotherapy-naive patients with advanced colorectal cancer scheduled to receive mFOLFOX6 were ...

Human natural killer (NK) cells are considered professional cytotoxic cells that are integrated into the effector branch of innate immunity during antiviral and antitumoral responses. The purpose of this study was to examine the peripheral distribution and expression of NK cell activation receptors from the fresh peripheral blood mononuclear cells of 30 breast cancer patients prior to any form ...

Monitoring Markov Dependent Observations with a Log-Likelihood Based CUSUM Shabnam Mousavi and Marion R. Reynolds, Jr. Department of Statistics, The Pennsylvania State University, University Park, PA 16802-2111, U.S.A., Max Planck Institute for Human Development, Lentzeallee 94, 14195 Berlin, Germany, Departments of Statistics and Forestry, Virginia Polytechnic Institute and State University, B...

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439 1. Experiments with Animals . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 442 2. Studies with Humans . . . . . . . . . . . . . . . . . . . . . . . . . . ...

The DAO-type white dwarf LS V+4621 is the hydrogen-rich central star of the possible planetary nebula Sh 2-216. We have taken high-resolution, high-S/N ultraviolet spectra with STIS aboard the HST and FUSE in order to constrain its photospheric parameters. A detailed spectral analysis by means of state-of-the-art NLTE model-atmosphere techniques is presented which includes the determination the...

BACKGROUND AND PURPOSE Intracranial angioplasty and stent placement are used to treat intracranial atherosclerotic disease. The 2 interventions have not been directly compared. MATERIALS AND METHODS This was a single-center, single-operator registry of consecutive, symptomatic subjects receiving treatment (angioplasty, BMS, or WS, chosen based on safety as judged by the operator). After Novem...

ADVERTISEMENT RETURN TO ARTICLES ASAPEditorialNEXTChange Is the Only Constant: A Virtual Issue on Contemporary CatalysisShelley Minteer*Shelley Minteer*Email: [email protected]More by Shelley Minteerhttps://orcid.org/0000-0002-5788-2249, Stephanie L. Brock*Stephanie Brock*Email: Brockhttps://orcid.org/0000-0002-0439-302X, Géraldine Masson*Géraldine Masson*Email: Massonhttps://orcid.org/0000-000...

The paper constructs a generalized version of universal traversing sequences. The generalization preserves the features of the universal traversing sequences that make them attractive for applications to derandomizations and space-bounded computation. For every n, a sequence is constructed that is used by a finite-automaton with 0(1) states in order to traverse all the n-vertex labeled undirect...