نتایج جستجو برای: 021 and 051

تعداد نتایج: 16828638  

Journal: :Applied health economics and health policy 2018
Emily Eaton Turner Michelle Jenks Rachael McCool Chris Marshall Liesl Millar Hannah Wood Alison Peel Joyce Craig Andrew J Sims

Memokath-051 is a thermo-expandable, nickel-titanium alloy spiral stent used to treat ureteric obstruction resulting from malignant or benign strictures. The National Institute for Health and Care Excellence (NICE) selected Memokath-051 for evaluation. The company, PNN Medical, claimed Memokath-051 has clinical superiority and cost savings compared with double-J stents. It identified five studi...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2007
Koichi Omura Takashi Nakazawa Takahiro Sato Takashi Iwanaga Osamu Nagata

In humans, orally administered 4-(5-pyridin-4-yl-1H-[1,2,4]triazol-3-yl) pyridine-2-carbonitrile (FYX-051) is excreted mainly as triazole N(1)- and N(2)-glucuronides in urine. It is important to determine the enzyme(s) that catalyze the metabolism of a new drug to estimate individual differences and/or drug-drug interactions. Therefore, the characterization and mechanism of these glucuronidatio...

2016
Gabriele Grandi Jelena Loncarski Milan Srndovic

Gabriele Grandi 1,*, Jelena Loncarski 2 and Milan Srndovic 1 1 Department of Electrical, Electronic, and Information Engineering, University of Bologna, Viale Risorgimento 2, Bologna 40136, Italy; [email protected] 2 Department of Engineering Sciences, Ångström Laboratory, Uppsala University, Lägerhyddsvägen 1, Box 534, Uppsala S-751 21, Sweden; [email protected] * Correspo...

2011
Suvrit Sra

Within the unmanageably large class of nonconvex optimization, we consider the rich subclass of nonsmooth problems having composite objectives (this includes the extensively studied convex, composite objective problems as a special case). For this subclass, we introduce a powerful, new framework that permits asymptotically non-vanishing perturbations. In particular, we develop perturbation-base...

2000
Jean-Louis VERGER-GAUGRY Jean-Pierre GAZEAU

We investigate in a geometrical way the sieving process of 021 β 3 for obtaining the Delone set 0 β 4 051 β 3 of β integers where β is a Perron number in the context of linear asymptotic invariants associated with a canonical inductive system constructed from β . When β is a Pisot number, we exhibit a canonical cut-and-project scheme, a model set associated with 0 β and so prove that it is a Me...

2004
Robert B. Tompkin

The environment in which foods are prepared and handled can have significant impact on microbiological safety and quality, particularly for ready-to-eat foods. Outbreaks associated with Listeria monocytogenes and salmonellae have led to an increasing awareness that certain pathogens can persist in food processing environments, contaminate foods as they are being processed and lead to foodborne ...

Journal: :Pediatric Critical Care Medicine 2018

Journal: :Anesthesiology 2015
Francis J Golder Scott Dax Santhosh M Baby Ryan Gruber Toshinori Hoshi Courtney Ideo Andrew Kennedy Sean Peng Veljko Puskovic David Ritchie Richard Woodward Robert L Wardle Michael R Van Scott James C Mannion D Euan MacIntyre

BACKGROUND The authors describe the preclinical pharmacological properties of GAL-021, a novel peripheral chemoreceptor modulator. METHODS The ventilatory effects of GAL-021 were characterized using tracheal pneumotachometry (n = 4 to 6), plethysmography (n = 5 to 6), arterial blood gas analyses (n = 6 to 11), and nasal capnography (n = 3 to 4) in naive animals and those subjected to morphine...

Journal: :Pediatric Critical Care Medicine 2018

Journal: :Pediatric Critical Care Medicine 2018

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