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Sepia ink oligopeptide (SIO) is a tripeptide extracted from Sepia ink. To test the hypothesis that SIO inhibits prostate cancer by inducing apoptosis, the effects of SIO on the proliferation of three human prostate cancer cell lines were examined using a CCK-8 assay. SIO significantly inhibited the proliferation of DU-145, PC-3 and LNCaP cells in a time- and dose-dependent manner. Flow cytometr...
این پایان نامه برگرفته از مقاله زیر است g-frames and g-riesz bases, j. math. anal. appl. 322 (2006) 437-452."
in this thesis we will present three topics. we define approximate fixed points in fuzzy normed spaces. also we obtain some necessary and sufficient conditions on the existence of? -fixed points for ? > 0. at the continue some results about approximate fixed points for a class of non-expansive maps on g-metric spaces are obtained and we define approximate fixed points in partial metric spa...
Phosphoinositide 3-kinases g and d (PI3Kg and PI3Kd) are expressed in rheumatoid arthritis (RA) synovium and regulate innate and adaptive immune responses. We determined the effect of a potent PI3Kd,g inhibitor, IPI-145, in two preclinical models of RA. IPI-145 was administered orally in rat adjuvantinduced arthritis (AA) and intraperitoneally in mouse collageninduced arthritis (CIA). Efficacy ...
Canonical Wnt signaling plays a critical role in stem cell maintenance in epithelial homeostasis and carcinogenesis. Here, we show that in the mouse this role is critically mediated by Bcl9/Bcl9l, the mammalian homologues of Legless, which in Drosophila is required for Armadillo/beta-catenin signaling. Conditional ablation of Bcl9/Bcl9l in the intestinal epithelium, where the essential role of ...
A graph G = (V,E) is a 3-leaf power iff there exists a tree T whose leaves are V and such that (u, v) ∈ E iff u and v are at distance at most 3 in T . The 3-leaf power graph edge modification problems, i.e. edition (also known as the closest 3-leaf power), completion and edge-deletion, are FTP when parameterized by the size of the edge set modification. However polynomial kernel was known for n...
GENERAL CIRCULATION MODEL. R. J. Wilson, R.M. Haberle, J. Noble, A.F.C. Bridger, J. Schaeffer, J.R. Barnes, and B.A. Cantor. NOAA/Geophysical Fluid Dynamics Laboratory, Princeton, NJ 08542 ([email protected]), Space Science Division, NASA/Ames Research Center, Moffett Field CA, 94035, College of Oceanic and Atmospheric Sciences, Oregon State University, Corvallis, OR. 97331, Malin Space Scie...
section{introduction} the concept of {sl cartan geometry} appeared at the beginning of the twentieth century, when {e}lie cartan was working on the so-called {sl equivalence problem}, the aim of which is to determine whether two given geometric structures can be mapped bijectively onto each other by some diffeomorphism. this problem can be considered in many different contexts, such as ...
Indaziflam {N-[(1R, 2S)-2,3-dihydro-2,6-dimethyl-1H-inden-1-yl]-6-[(1RS)-1fluoroethyl]-1,3,5-triazine-2,4-diamine} is a new pre-emergence herbicide recently registered for a broad spectrum weed control in Florida citrus. Experiments were conducted to evaluate leaching of indaziflam applied at 73 and 145 g ai ha(-1) in Florida Candler soil under simulated rainfall of 5, 10, and 15 cm ha(-1). Ind...
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