BACKGROUND Up to now, prostate-specific membrane antigen (PSMA)-targeted radionuclide therapy mainly focused on β-emitting radionuclides. Herein, two new 213Bi-labeled agents for PSMA-targeted α therapy of prostate cancer (PCa) are reported. METHODS The biodistribution of 213Bi-labeled small-molecule inhibitor PSMA I&T and nanobody JVZ-008 was evaluated in mice bearing PSMA-positive LNCaP xen...

Major histocompatibility complex class I-related chain A (MICA) is located at 46 kb centromeric of HLA-B. It is highly polymorphic and interacts with NKG2D, its receptor on the surface of NK, Tgammadelta and T CD8 lymphocytes. Data on MICA polymorphism in different populations are still limited. Our aim was to establish allelic diversity of MICA gene and linkage disequilibrium with HLA-B in our...

008 ©2011 Society For Biomaterials

0895-7061/07/$32.00 doi:10.1016/j.amjhyper.2007.05.011 risk of the secondary, composite endpoint (death, stroke, or myocardial infarction) was determined by diabetes (P .008) and CIMT (P .010). Nearly 99% of patients with “low CIMT” ( 1.13 mm) survived for 5 years, versus 78% with “high CIMT” 1.13 mm (log-rank test; P .001). For the secondary, composite endpoint (death, stroke, or myocardial in...

We note that the Chinese remainder theorem implies that this group is isomorphic with the cylic group of order 30, Z30. 31 is prime so the only abelian group of order 31 is Z31. 32 = 2. So there are many possibilities corresponding to all of the ways we can write m1 +m2 + ...+mr = 5 with m1 ≥ m2 ≥ ... ≥ mr. The solutions are 5 = 5 which corresponds to Z32, 4 ≥ 1 giving Z16 ×Z2, 3 ≥ 2 giving Z8 ...