The following ar ticle is based on the Outstanding Young Investigator Award presentation given by Ju Li on April 19, 2006, at the Materials Research Society Spring Meeting in San Francisco. Li received the award “for his innovative work on the atomistic and first principles modeling of nanoindentation and ideal strength in revealing the genesis of ma te rials deformation and fracture.” Defect n...

rials (Figure and eFigure 2). Smartphone-attached “laboratory on chip” (LOC) devices with modular microfluidic chips based on optoelectrowetting technology can perform sample preparation and detection steps in a simple and automated manner; LOC devices to run capillary electrophoresis, real-time polymerase chain reaction, flow cytometry, enzymatic assays, biomarker screening, and immunoassays h...

BACKGROUND It is estimated that major depression disorders constitute 8.2% of years lived with disability (YLDs) globally. The repetitive Transcranial Magnetic Stimulation (rTMS) and Electroconvulsive Therapy (ECT) are two relative common interventions to treat major depressive disorders, especially for treatment resistant depression. In this study the cost- effectiveness and cost-utility of rT...

Background: The quality of life in patients with chronic obstructive pulmonary disease (COPD) is associated with poor pulmonary function, respiratory symptoms, incapacity to perform daily activities, as well as mental and cognitive disorders. Although there exists some evidence regarding the effect of socioeconomic status on the quality of life in the general population and those with chronic d...

INTRODUCTION Screening can prevent colorectal cancer from becoming advanced by early detection of precancerous lesions. Cost-effectiveness analysis of colorectal cancer screening methods is highly necessary due to increased prevalence, decreased age at onset and the limited budget in Iran. METHODS Methods of screening currently available in Iran were selected. A systematic search revealed the...

BACKGROUND Traumatic Brain Injuries (TBIs) as a result of traffic accidents are one of the major causes of deaths, which lead to the loss of individuals' productive and working years of life. OBJECTIVES This study aimed to calculate the economic burden of traumatic brain injuries in fatal crashes at Shahid Rajaei Trauma Hospital, Shiraz, Iran for a period of five years. PATIENTS AND METHODS...